Aptamer-Mediated Up-conversion Core/MOF Shell Nanocomposites for Targeted Drug Delivery and Cell Imaging
文献类型：期刊论文
| 作者 | Deng,Kerong; Hou,Zhiyao; Li,Xuejiao; Li,Chunxia; Zhang,Yuanxin; Deng,Xiaoran; Cheng,Ziyong; Lin,Jun |
| 刊名 | scientific reports
 |
| 出版日期 | 2015 |
| 卷号 | 5页码:7851 |
| 关键词 | METAL-ORGANIC FRAMEWORKS PHOTOTHERMAL THERAPY NANOPARTICLES CANCER NANOMATERIALS ENCAPSULATION CHALLENGES SILICA PROBES |
| 通讯作者 | lin,j |
| 英文摘要 | multifunctional nanocarriers for targeted bioimaging and drug delivery have attracted much attention in early diagnosis and therapy of cancer. in this work, we develop a novel aptamer-guided nanocarrier based on the mesoporous metal-organic framework (mof) shell and up-conversion luminescent nayf4:yb3+/er3+ nanoparticles (ucnps) core for the first time to achieve these goals. these ucnps, chosen as optical labels in biological assays and medical imaging, could emit strong green emission under 980 nm laser. the mof structure based on iron (iii) carboxylate materials [mil-100 (fe)] possesses high porosity and non-toxicity, which is of great value as nanocarriers for drug storage/delivery. as a unique nanoplatform, the hybrid inorganic-organic drug delivery vehicles show great promising for simultaneous targeted labeling and therapy of cancer cells. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/64846]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Deng,Kerong,Hou,Zhiyao,Li,Xuejiao,et al. Aptamer-Mediated Up-conversion Core/MOF Shell Nanocomposites for Targeted Drug Delivery and Cell Imaging[J]. scientific reports,2015,5:7851. |
| APA | Deng,Kerong.,Hou,Zhiyao.,Li,Xuejiao.,Li,Chunxia.,Zhang,Yuanxin.,...&Lin,Jun.(2015).Aptamer-Mediated Up-conversion Core/MOF Shell Nanocomposites for Targeted Drug Delivery and Cell Imaging.scientific reports,5,7851. |
| MLA | Deng,Kerong,et al."Aptamer-Mediated Up-conversion Core/MOF Shell Nanocomposites for Targeted Drug Delivery and Cell Imaging".scientific reports 5(2015):7851. |
入库方式： OAI收割
来源：长春应用化学研究所
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