New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica
文献类型：期刊论文
| 作者 | Li, Yun; Yang, Jiajia; Jin, Jing; Sun, Xiaoli; Wang, Longxing; Chen, Jiping |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2014-04-11 |
| 卷号 | 1337期号:1页码:133-139 |
| 关键词 | Dendritic polymer-modified silica Mixed-mode chromatography Reversed phase Anion-exchange HILIC Acidic or polar molecules |
| 通讯作者 | 陈吉平 |
| 英文摘要 | a novel dendritic polymer-modified silica (dps) stationary phase was prepared by a divergent synthesis scheme starting from propylamine on silica by consecutive amine-epoxy reactions with 1,4butanedioldiglycidyl ether and aniline. both elemental analysis and infrared spectra data shows the successful growth of dendritic polymer on silica particles. the carbon and nitrogen contents increased with an increasing number of reaction cycles and achieved 25.2% and 2.1% (w/w) after 11 reaction cycles. the combination of a phenyl ring with a quaternary ammonium, or a tertiary amine at the branch point along with embedded polar functionalities (including ether and hydroxyl groups) in the branch, generated hydrophobic, electrostatic, as well as hydrophilic interactive domains. depending on solute structure and mobile phase composition, the dps stationary phase provided multiple retention mechanisms, including reversed phase (rp), anion-exchange (aex), and hydrophilic interactions. the rp capability achieved separation of polycyclic aromatic hydrocarbons. basic, neutral and acidic molecules were well separated under rp/aex mixed mode. effective separation of small polar compounds (such as nucleobases and nucleosides) was also obtained under hydrophilic interaction liquid chromatography (hilic) mode. (c) 2014 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | hydrophilic-interaction chromatography ; interaction liquid-chromatography ; tandem mass-spectrometry ; cation-exchange ; nucleic-acids ; hplc column ; separation ; retention ; nucleosides ; peptides |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000334082200017 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/144064]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Liaoning, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yun,Yang, Jiajia,Jin, Jing,et al. New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica[J]. journal of chromatography a,2014,1337(1):133-139. |
| APA | Li, Yun,Yang, Jiajia,Jin, Jing,Sun, Xiaoli,Wang, Longxing,&Chen, Jiping.(2014).New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica.journal of chromatography a,1337(1),133-139. |
| MLA | Li, Yun,et al."New reversed-phase/anion-exchange/hydrophilic interaction mixed-mode stationary phase based on dendritic polymer-modified porous silica".journal of chromatography a 1337.1(2014):133-139. |
入库方式： OAI收割
来源：大连化学物理研究所
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