Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry
文献类型：期刊论文
| 作者 | Qiao, Xiaoqiang1,2; Wang, Rui1,2,3; Yan, Hongyuan1,2; Wang, Tao1,2; Zhao, Qun3; Zhang, Lihua3; Zhang, Yukui3 |
| 刊名 | rapid communications in mass spectrometry
 |
| 出版日期 | 2014-02-15 |
| 卷号 | 28期号:3页码:256-264 |
| 通讯作者 | 乔晓强 ; 张丽华 |
| 英文摘要 | rationalechemical derivatization is a very promising technique for improving analysis of peptides by mass spectrometry (ms). in this study, a novel kind of imidazolium-based aromatic quaternary ammonium tag, 1-[3-[(2-iodo-1-oxoethyl)amino]propyl]-3-butylimidazolium bromide (ipbi), designed with strong gas-phase basicity and a permanent positive charge, was firstly synthesized and further used for derivatization of cysteinyl-peptides with improved ionization efficiency and higher charge states. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences ; technology |
| 学科主题 | 物理化学 |
| 类目[WOS] | biochemical research methods ; chemistry, analytical ; spectroscopy |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry ; spectroscopy |
| 关键词[WOS] | electron-transfer dissociation ; carboxy group derivatization ; n-terminal derivatization ; maldi-tof ms ; chemical derivatization ; signal enhancement ; bottom-up ; liquid ; phosphopeptides ; ionization |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000328823200003 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/144440]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Hebei Univ, Key Lab Pharmaceut Qual Control Hebei Prov, Baoding 071002, Peoples R China 2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiao, Xiaoqiang,Wang, Rui,Yan, Hongyuan,et al. Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry[J]. rapid communications in mass spectrometry,2014,28(3):256-264. |
| APA | Qiao, Xiaoqiang.,Wang, Rui.,Yan, Hongyuan.,Wang, Tao.,Zhao, Qun.,...&Zhang, Yukui.(2014).Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry.rapid communications in mass spectrometry,28(3),256-264. |
| MLA | Qiao, Xiaoqiang,et al."Development of a novel imidazolium-based aromatic quaternary ammonium tag: Synthesis and application to the efficient analysis of cysteinyl-peptides by mass spectrometry".rapid communications in mass spectrometry 28.3(2014):256-264. |
入库方式： OAI收割
来源：大连化学物理研究所
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