Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics
文献类型：期刊论文
| 作者 | Cheng, Chang-Li; Zhang, Ming-Zhen; Zhao, Guang-Jiu |
| 刊名 | rsc advances
 |
| 出版日期 | 2014 |
| 卷号 | 4期号:13页码:6513-6516 |
| 英文摘要 | green fluorescent protein (gfp) is used as a biosensor for protein-protein interactions, co-translational folding and localization of different structures in cells, in which the mechanical stability and thermal conductivity of the beta-barrels play a vital role. in this work, we first explore themechanical and thermal properties of beta-barrels in gfp by using the molecular dynamics simulations. our results show that the beta-barrel is destabilized once one strand is detached. moreover, we also observe that the temperature relaxation processes of an unfolded state and the native state are nearly the same. our dynamics simulations improve the understanding of mechanical stability of beta-barrels and help to find nanoscale mechanism controlling energy transport in biomolecules. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | anisotropic deformation ; infrared-spectroscopy ; complex-formation ; gfp ; pathways ; simulation ; landscape ; light |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000329931000023 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/145463]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cheng, Chang-Li,Zhang, Ming-Zhen,Zhao, Guang-Jiu. Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics[J]. rsc advances,2014,4(13):6513-6516. |
| APA | Cheng, Chang-Li,Zhang, Ming-Zhen,&Zhao, Guang-Jiu.(2014).Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics.rsc advances,4(13),6513-6516. |
| MLA | Cheng, Chang-Li,et al."Mechanical stability and thermal conductivity of beta-barrel in green fluorescent protein by steered molecular dynamics".rsc advances 4.13(2014):6513-6516. |
入库方式： OAI收割
来源：大连化学物理研究所
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