Discovery of N-methyltetrahydroprotoberberines with kappa-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography
文献类型：期刊论文
| 作者 | Zhang, Yan1; Wang, Chaoran2; Guo, Zhimou2; Zhang, Xiuli2; Wang, Zhiwei1; Liang, Xinmiao2,3; Civelli, Olivier1,4,5 |
| 刊名 | journal of ethnopharmacology
 |
| 出版日期 | 2014-09-29 |
| 卷号 | 155期号:3页码:1597-1602 |
| 关键词 | GPCR TCMs 2D separation Corydalis yanhusuo WT Wang kappa-opioid receptor |
| 英文摘要 | ethnopharmacological relevance: the need for an efficacious analgesic without unwanted side effects is urgent. kappa-opioid receptor agonists are known to exhibit potent analgesic effects and elicited fewer side effects than other opioid agonists. thus in this study we chose the kappa-opioid receptor as the target to identify the active components from traditional chinese medicines (tcms). |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | plant sciences ; chemistry, medicinal ; integrative & complementary medicine ; pharmacology & pharmacy |
| 研究领域[WOS] | plant sciences ; pharmacology & pharmacy ; integrative & complementary medicine |
| 关键词[WOS] | natural-products ; alkaloids ; purification ; separation ; phase ; medicine ; system ; column ; pain |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000343380300023 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/145544]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Calif Irvine, Dept Pharmacol, Irvine, CA 92697 USA 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 3.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China 4.Univ Calif Irvine, Dept Pharmacol Sci, Irvine, CA 92697 USA 5.Univ Calif Irvine, Dept Dev & Cell Biol, Irvine, CA 92697 USA |
| 推荐引用方式 GB/T 7714 | Zhang, Yan,Wang, Chaoran,Guo, Zhimou,et al. Discovery of N-methyltetrahydroprotoberberines with kappa-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography[J]. journal of ethnopharmacology,2014,155(3):1597-1602. |
| APA | Zhang, Yan.,Wang, Chaoran.,Guo, Zhimou.,Zhang, Xiuli.,Wang, Zhiwei.,...&Civelli, Olivier.(2014).Discovery of N-methyltetrahydroprotoberberines with kappa-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography.journal of ethnopharmacology,155(3),1597-1602. |
| MLA | Zhang, Yan,et al."Discovery of N-methyltetrahydroprotoberberines with kappa-opioid receptor agonists-opioid receptor agonist activities from corydalis yanhusuo W. T. Wang by using two-dimensional liquid chromatography".journal of ethnopharmacology 155.3(2014):1597-1602. |
入库方式： OAI收割
来源：大连化学物理研究所
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