Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry
文献类型:期刊论文
作者 | Qiao, Xiaoqiang1,2; Wang, Rui1,2,3; Li, Guangyue4; Yan, Hongyuan1,2; Zhou, Yuan3; Zhang, Lihua3; Zhang, Yukui3 |
刊名 | analyst
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出版日期 | 2014 |
卷号 | 139期号:4页码:705-708 |
英文摘要 | new types of imidazolium-based iodoacetamide tags were designed, synthesized and further exploited for cysteinyl-peptide analysis with superior labeling efficiency, high stability, improved ionization efficiency, and increased charge states bymass spectrometry. for the first time, the effects of these kinds of tags on the mass spectrometry performance of the derivatized peptides were investigated, which is of great importance to help us design more efficient tags for the analysis of peptides or proteins, especially for those with low abundance. |
WOS标题词 | science & technology ; physical sciences |
类目[WOS] | chemistry, analytical |
研究领域[WOS] | chemistry |
关键词[WOS] | electron-transfer dissociation ; carboxy group derivatization ; quaternary ammonium tag ; amino-acids ; peptides ; matrix ; ionization ; reagents ; phosphopeptides ; quantitation |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000330042500002 |
公开日期 | 2016-05-09 |
源URL | [http://cas-ir.dicp.ac.cn/handle/321008/145779] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Hebei Univ, Minist Educ, Key Lab Med Chem & Mol Diag, Baoding 071002, Peoples R China 2.Hebei Univ, Coll Pharmaceut Sci, Baoding 071002, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog Res & Anal Ctr, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 4.Hebei United Univ, Coll Chem Engn, Tangshan 063009, Peoples R China |
推荐引用方式 GB/T 7714 | Qiao, Xiaoqiang,Wang, Rui,Li, Guangyue,et al. Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry[J]. analyst,2014,139(4):705-708. |
APA | Qiao, Xiaoqiang.,Wang, Rui.,Li, Guangyue.,Yan, Hongyuan.,Zhou, Yuan.,...&Zhang, Yukui.(2014).Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry.analyst,139(4),705-708. |
MLA | Qiao, Xiaoqiang,et al."Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinylpeptide analysis by mass spectrometry".analyst 139.4(2014):705-708. |
入库方式: OAI收割
来源:大连化学物理研究所
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