Protein-protein interaction network of the marine microalga Tetraselmis subcordiformis: prediction and application for starch metabolism analysis
文献类型：期刊论文
| 作者 | Ji, Chaofan1; Cao, Xupeng2; Yao, Changhong2; Xue, Song2; Xiu, Zhilong1 |
| 刊名 | journal of industrial microbiology & biotechnology
 |
| 出版日期 | 2014-08-01 |
| 卷号 | 41期号:8页码:1287-1296 |
| 关键词 | Chlorophyceae Interolog Ortholog Post-translational modification |
| 英文摘要 | under stressful conditions, the non-model marine microalga tetraselmis subcordiformis can accumulate a substantial amount of starch, making it a potential feedstock for the production of fuel ethanol. investigating the interactions of the enzymes and the regulatory factors involved in starch metabolism will provide potential genetic manipulation targets for optimising the starch productivity of t. subcordiformis. for this reason, the proteome of t. subcordiformis was utilised to predict the first protein-protein interaction (ppi) network for this marine alga based on orthologous interactions, mainly from the general ppi repositories. different methods were introduced to evaluate the credibility of the predicted interactome, including the confidence value of each ppi pair and pfam-based and subcellular location-based enrichment analysis. functional subnetworks analysis suggested that the two enzymes involved in starch metabolism, starch phosphorylase and trehalose-phosphate synthase may be the potential ideal genetic engineering targets. |
| WOS标题词 | science & technology ; life sciences & biomedicine |
| 类目[WOS] | biotechnology & applied microbiology |
| 研究领域[WOS] | biotechnology & applied microbiology |
| 关键词[WOS] | biosynthetic-enzymes ; interaction database ; amyloplasts ; complexes ; associate |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000339385400012 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/145854]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Dalian Univ Technol, Sch Life Sci & Biotechnol, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Marine Bioprod Engn Grp, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ji, Chaofan,Cao, Xupeng,Yao, Changhong,et al. Protein-protein interaction network of the marine microalga Tetraselmis subcordiformis: prediction and application for starch metabolism analysis[J]. journal of industrial microbiology & biotechnology,2014,41(8):1287-1296. |
| APA | Ji, Chaofan,Cao, Xupeng,Yao, Changhong,Xue, Song,&Xiu, Zhilong.(2014).Protein-protein interaction network of the marine microalga Tetraselmis subcordiformis: prediction and application for starch metabolism analysis.journal of industrial microbiology & biotechnology,41(8),1287-1296. |
| MLA | Ji, Chaofan,et al."Protein-protein interaction network of the marine microalga Tetraselmis subcordiformis: prediction and application for starch metabolism analysis".journal of industrial microbiology & biotechnology 41.8(2014):1287-1296. |
入库方式： OAI收割
来源：大连化学物理研究所
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