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In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences

文献类型：期刊论文

作者Sun, Dongxue1; Zhu, Liangliang2; Xiao, Ling3; Xia, Yangliu4; Ge, Guangbo4; Cao, Yunfeng4; Wu, Yan2; Yin, Jun1; Yang, Ling4
刊名xenobiotica
出版日期2014-11-01
卷号44期号:11页码:988-995
关键词Armillarisin A liver microsomal glucuronidation species difference UDP-glucuronosyltranferases
英文摘要1. this study is performed to investigate liver microsomal glucuronidation of armillarisin a (a.a), an effective cholagogue drug, aiming at characterizing the involved udp-glucuronosyltranferases (ugt) and revealing potential species differences.
WOS标题词science & technology ; life sciences & biomedicine
类目[WOS]pharmacology & pharmacy ; toxicology
研究领域[WOS]pharmacology & pharmacy ; toxicology
关键词[WOS]tandem mass-spectrometry ; messenger-rna expression ; human liver ; intestinal glucuronidation ; drug glucuronidation ; cytochrome-p450 ; inhibition ; metabolism ; isoforms ; identification
收录类别SCI
语种英语
WOS记录号WOS:000343080900004
公开日期2016-05-09
源URL[http://cas-ir.dicp.ac.cn/handle/321008/145893]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
作者单位1.Shenyang Pharmaceut Univ, Sch Tradit Chinese Med, Dept Tradit Chinese Med Resources, Shenyang, Peoples R China
2.Anqing Normal Univ, Sch Life Sci, Lab Drug & Food Safety Evaluat, Anqing, Peoples R China
3.Anqing Normal Univ, Lab Resources & Environm, Anqing, Peoples R China
4.Chinese Acad Sci, Dalian Inst Chem Phys, Lab Pharmaceut Resource Discovery, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714		 Sun, Dongxue,Zhu, Liangliang,Xiao, Ling,et al. In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences[J]. xenobiotica,2014,44(11):988-995.
APA Sun, Dongxue.,Zhu, Liangliang.,Xiao, Ling.,Xia, Yangliu.,Ge, Guangbo.,...&Yang, Ling.(2014).In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences.xenobiotica,44(11),988-995.
MLA Sun, Dongxue,et al."In vitro glucuronidation of Armillarisin A: UDP-glucuronosyltransferase 1A9 acts as a major contributor and significant species differences".xenobiotica 44.11(2014):988-995.

入库方式： OAI收割

来源：大连化学物理研究所

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