pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate
文献类型：期刊论文
| 作者 | Liu, Lei1,2; Yang, Dapeng1,3; Li, Peng1 |
| 刊名 | journal of physical chemistry b
 |
| 出版日期 | 2014-10-09 |
| 卷号 | 118期号:40页码:11707-11714 |
| 英文摘要 | the ph-related fluorescence quenching mechanism of 2-amino-4-hydroxypteridine (pterin), a biologic functional molecule, in the presence of acetate ion has been fully investigated for the first time. using a combined experimental and theoretical approach, we discover that the fluorescence quenching observed in acid condition originated from a barrierless excited-state proton-transfer process. the proton on the acid form of pterin is transferred to acetate after photoexcitation. the hydrogen-bonding patterns are found to change with the ph values that govern the occurrence of excited-state proton transfer (espt). as revealed by investigating the excitation and relaxation processes of pterin, this espt process shows impressive site specificity intrinsically due to the photoinduced acidic center shifting. the experimentally observed fluorescence quenching and lifetime shortening of pterin in acid condition are thus attributed to the site-specific proton transfer from the n5 site. pterin exists extensively in living organisms and has been found to show favorable proton-donating ability, which may transfer its proton to biofunctional molecules with hydrogen-accepting groups and induce related bioeffects. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, physical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | 2'-deoxyguanosine 5'-monophosphate ; electron-transfer ; aqueous-solution ; folic-acid ; fluorescence ; mechanism ; tetrahydrobiopterin ; biosynthesis ; metabolism ; pteridines |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000343016000012 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/145922]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China 2.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China 3.North China Univ Water Resources & Elect Power, Phys Lab, Zhengzhou 450045, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Lei,Yang, Dapeng,Li, Peng. pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate[J]. journal of physical chemistry b,2014,118(40):11707-11714. |
| APA | Liu, Lei,Yang, Dapeng,&Li, Peng.(2014).pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate.journal of physical chemistry b,118(40),11707-11714. |
| MLA | Liu, Lei,et al."pH-Related and Site-Specific Excited-State Proton Transfer from Pterin to Acetate".journal of physical chemistry b 118.40(2014):11707-11714. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。