Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones
文献类型：期刊论文
| 作者 | Huang, Wen-Xue1,2; Wu, Bo2; Gao, Xiang2; Chen, Mu-Wang2; Wang, Baomin1; Zhou, Yong-Gui2 |
| 刊名 | organic letters
 |
| 出版日期 | 2015-04-03 |
| 卷号 | 17期号:7页码:1640-1643 |
| 英文摘要 | the selective hydrogenation of 3-hydroxypyridinium salts has been achieved using a homogeneous iridium catalyst, providing a direct access to 2- and 4-substituted piperidin-3-one derivatives with high yields, which are important organic synthetic intermediates and the prevalent structural motifs in pharmaceutical agents. mild reaction conditions, high chemoselectivity, and easy scalability make this reaction highly practical for the synthesis of piperidin-3-ones. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | n-heteroaromatic compounds ; asymmetric hydrogenation ; pyridinium salts ; aqueous-phase ; substituted piperidines ; phenol hydrogenation ; efficient ; derivatives ; nanoparticles ; reduction |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000352463200006 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/146168]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Dalian Univ Technol, Sch Pharmaceut Sci & Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Wen-Xue,Wu, Bo,Gao, Xiang,et al. Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones[J]. organic letters,2015,17(7):1640-1643. |
| APA | Huang, Wen-Xue,Wu, Bo,Gao, Xiang,Chen, Mu-Wang,Wang, Baomin,&Zhou, Yong-Gui.(2015).Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones.organic letters,17(7),1640-1643. |
| MLA | Huang, Wen-Xue,et al."Iridium-Catalyzed Selective Hydrogenation of 3-Hydroxypyridinium Salts: A Facile Synthesis of Piperidin-3-ones".organic letters 17.7(2015):1640-1643. |
入库方式： OAI收割
来源：大连化学物理研究所
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