Divergent and concise total syntheses of dihydrochalcones and 5-deoxyflavones recently isolated from Tacca species and Mimosa diplotricha
文献类型：期刊论文
| 作者 | Sum, Tze Han1; Sum, Tze Jing1; Stokes, Jamie E.1; Galloway, Warren R. J. D.1; Spring, David R.1,2 |
| 刊名 | tetrahedron
 |
| 出版日期 | 2015-07-01 |
| 卷号 | 71期号:26-27页码:4557-4564 |
| 关键词 | Natural product synthesis Flavonoids Dihydrochalcones Deoxyflavones Divergent synthesis |
| 英文摘要 | dihydrochalcones and 5-deoxyflavones are types of compounds possessing various biologically interesting properties. herein, we report the concise and divergent total syntheses of several naturally occurring dihydrochalcones and 5-deoxyflavones from readily available starting materials. the divergent strategy is based around manipulation of a common chalcone scaffold and features application of algar flynn-oyamada oxidation and benzoquinone c-h activation methodologies. these are the first reported total syntheses of these biologically interesting compounds and the concise and flexible route should be readily amenable to future analogue generation. furthermore, this work provides an illustration of the utility of divergent synthesis for the expedient and step-economical preparation of natural product libraries. (c) 2015 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | diversity-oriented synthesis ; inhibitors ; strategy ; flavonoids ; chalcones ; alkaloids ; quinones |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000356207700023 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/146311]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sum, Tze Han,Sum, Tze Jing,Stokes, Jamie E.,et al. Divergent and concise total syntheses of dihydrochalcones and 5-deoxyflavones recently isolated from Tacca species and Mimosa diplotricha[J]. tetrahedron,2015,71(26-27):4557-4564. |
| APA | Sum, Tze Han,Sum, Tze Jing,Stokes, Jamie E.,Galloway, Warren R. J. D.,&Spring, David R..(2015).Divergent and concise total syntheses of dihydrochalcones and 5-deoxyflavones recently isolated from Tacca species and Mimosa diplotricha.tetrahedron,71(26-27),4557-4564. |
| MLA | Sum, Tze Han,et al."Divergent and concise total syntheses of dihydrochalcones and 5-deoxyflavones recently isolated from Tacca species and Mimosa diplotricha".tetrahedron 71.26-27(2015):4557-4564. |
入库方式： OAI收割
来源：大连化学物理研究所
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