Fluorescence imaging of metal ions implicated in diseases
文献类型：期刊论文
| 作者 | Qian, Xuhong1; Xu, Zhaochao2 |
| 刊名 | chemical society reviews
 |
| 出版日期 | 2015 |
| 卷号 | 44期号:14页码:4487-4493 |
| 英文摘要 | metal ions play an important role in various biological processes, their abnormal homeostasis in cells is related to many diseases, such as neurodegenerative disease, cancer and diabetes. fluorescent imaging offers a unique route to detect metal ions in cells via a contactless and damage-free way with high spatial and temporal fidelity. consequently, it represents a promising method to advance the understanding of physiological and pathological functions of metal ions in cell biology. in this highlight article, we will discuss recent advances in fluorescent imaging of metal ions by small-molecule sensors for understanding the role of metals in related diseases. we will also discuss challenges and opportunities for the design of small-molecule sensors for fluorescent detection of cellular metal ions as a potential method for disease diagnosis. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | living cells ; oxidative stress ; aqueous-solution ; zinc ion ; hippocampal slices ; live cells ; sensor ; zn2+ ; probe ; indicator |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000357691200002 |
| 公开日期 | 2016-05-09 |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/146381]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem CAS, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qian, Xuhong,Xu, Zhaochao. Fluorescence imaging of metal ions implicated in diseases[J]. chemical society reviews,2015,44(14):4487-4493. |
| APA | Qian, Xuhong,&Xu, Zhaochao.(2015).Fluorescence imaging of metal ions implicated in diseases.chemical society reviews,44(14),4487-4493. |
| MLA | Qian, Xuhong,et al."Fluorescence imaging of metal ions implicated in diseases".chemical society reviews 44.14(2015):4487-4493. |
入库方式： OAI收割
来源：大连化学物理研究所
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