Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose
文献类型：期刊论文
| 作者 | Cao, Yujin1 ; Cheng, Tao1; Zhao, Guang1; Niu, Wei2; Guo, Jiantao2; Xian, Mo1; Liu, Huizhou1
|
| 刊名 | BMC BIOTECHNOLOGY
 |
| 出版日期 | 2016-03-08 |
| 卷号 | 16 |
| 关键词 | Hydroxy fatty acid Escherichia coli Fatty acid hydroxylase Acetyl-CoA carboxylase Acyl-CoA thioesterase Acyl-CoA synthetase |
| 英文摘要 | Background: Hydroxy fatty acids (HFAs) are valuable chemicals for a broad variety of applications. However, commercial production of HFAs has not been established so far due to the lack of low cost routes for their synthesis. Although the microbial transformation pathway of HFAs was extensively studied decades ago, these attempts mainly focused on converting fatty acids or vegetable oils to their hydroxyl counterparts. The use of a wider range of feedstocks to produce HFAs would reduce the dependence on oil crops and be expected to cut down the manufacturing cost. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology |
| 关键词[WOS] | BACILLUS-MEGATERIUM ; OLEIC-ACID ; WHOLE CELLS ; MONOOXYGENASE ; OXIDATION ; IDENTIFICATION ; BIOSYNTHESIS ; EXPRESSION ; P450 ; REGIOSELECTIVITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000371769200001 |
| 公开日期 | 2016-05-17 |
| 源URL | [http://ir.qibebt.ac.cn/handle/337004/8054]  |
| 专题 | 青岛生物能源与过程研究所_材料生物技术研究中心 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA |
| 推荐引用方式 GB/T 7714 | Cao, Yujin,Cheng, Tao,Zhao, Guang,et al. Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose[J]. BMC BIOTECHNOLOGY,2016,16. |
| APA | Cao, Yujin.,Cheng, Tao.,Zhao, Guang.,Niu, Wei.,Guo, Jiantao.,...&Liu, Huizhou.(2016).Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose.BMC BIOTECHNOLOGY,16. |
| MLA | Cao, Yujin,et al."Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose".BMC BIOTECHNOLOGY 16(2016). |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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