中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Fine-tuning the LSPR response of gold nanorod-polyaniline core-shell nanoparticles with high photothermal efficiency for cancer cell ablation

文献类型:期刊论文

作者Hou,Hui; Chen,Limei; He,Haili; Chen,Lizhen; Zhao,Zhenlu; Jin,Yongdong
刊名journal of materials chemistry b
出版日期2015
卷号3期号:26页码:5189-5196
关键词ENHANCED RAMAN-SCATTERING METAL NANOPARTICLES DRUG-DELIVERY SURFACE-PLASMONS QUANTUM DOTS THERAPY POLYMER NANOCRYSTALS NANOSTRUCTURES CHEMISTRY
通讯作者jin,yd
英文摘要gold nanorods (gnrs) with suitable aspect ratios have strong localized surface plasmon resonance (lspr) absorption and scattering in the 650-900 nm near-infrared region, which make them attractive for in vitro or in vivo imaging and photothermal cancer therapy. however, they often suffer from cytotoxicity and instability for practical applications, and therefore need further surface modification to solve these issues. in this study, gnrs coated with biocompatible polyaniline (pani) were used as a stable and highly efficient photothermal agent for cancer cell ablation. fine-tuning the lspr response of the gnr-pani core-shell nanoparticles via thickness-controlled coating of the pani nanoshells, optimizes the photothermal conversion efficiency of the agent. as a result of the contributions from the gnr core and pani shell, the capability of photothermal transduction of the resultant nanoparticles at 808 nm is greatly enhanced. after exposure to a continuous nir laser at 808 nm for similar to 5 min, cancer cells were efficiently ablated requiring only a very low laser flux of 0.6 w cm(-2), the lowest value reported to date for plasmonic nanostructures, showing the great potential for photothermal cancer therapy.
收录类别SCI
语种英语
WOS记录号WOS:000356964700008
公开日期2016-05-31
源URL[http://ir.ciac.jl.cn/handle/322003/65081]  
专题长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式
GB/T 7714
Hou,Hui,Chen,Limei,He,Haili,et al. Fine-tuning the LSPR response of gold nanorod-polyaniline core-shell nanoparticles with high photothermal efficiency for cancer cell ablation[J]. journal of materials chemistry b,2015,3(26):5189-5196.
APA Hou,Hui,Chen,Limei,He,Haili,Chen,Lizhen,Zhao,Zhenlu,&Jin,Yongdong.(2015).Fine-tuning the LSPR response of gold nanorod-polyaniline core-shell nanoparticles with high photothermal efficiency for cancer cell ablation.journal of materials chemistry b,3(26),5189-5196.
MLA Hou,Hui,et al."Fine-tuning the LSPR response of gold nanorod-polyaniline core-shell nanoparticles with high photothermal efficiency for cancer cell ablation".journal of materials chemistry b 3.26(2015):5189-5196.

入库方式: OAI收割

来源:长春应用化学研究所

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