Enzyme-regulated the changes of pH values for assembling a colorimetric and multistage interconnection logic network with multiple readouts
文献类型：期刊论文
| 作者 | Huang,Yanyan; Ran,Xiang; Lin,Youhui; Ren,Jinsong; Qu,Xiaogang |
| 刊名 | analytica chimica acta
 |
| 出版日期 | 2015 |
| 卷号 | 870页码:92-98 |
| 关键词 | DNA NANOSTRUCTURES MOLECULAR LOGIC GATES NANOPARTICLES OPERATIONS DEVICES INTEGRATION ELEMENTS SCALE RNA |
| 通讯作者 | ren,js |
| 英文摘要 | based on enzymatic reactions-triggered changes of ph values and biocomputing, a novel and multistage interconnection biological network with multiple easy-detectable signal outputs has been developed. compared with traditional chemical computing, the enzyme-based biological system could overcome the interference between reactions or the incompatibility of individual computing gates and offer a unique opportunity to assemble multicomponent/multifunctional logic circuitries. our system included four enzyme inputs: beta-galactosidase (beta-gal), glucose oxidase (gox), esterase (est) and urease (ur). with the assistance of two signal transducers (gold nanoparticles and acid-base indicators) or ph meter, the outputs of the biological network could be conveniently read by the naked eyes. in contrast to current methods, the approach present here could realize cost-effective, label-free and colorimetric logic operations without complicated instrument. by designing a series of boolean logic operations, we could logically make judgment of the compositions of the samples on the basis of visual output signals. our work offered a promising paradigm for future biological computing technology and might be highly useful in future intelligent diagnostics, prodrug activation, smart drug delivery, process control, and electronic applications. (c) 2015 elsevier b.v. all rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000351778600009 |
| 公开日期 | 2016-05-31 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/65121]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Huang,Yanyan,Ran,Xiang,Lin,Youhui,et al. Enzyme-regulated the changes of pH values for assembling a colorimetric and multistage interconnection logic network with multiple readouts[J]. analytica chimica acta,2015,870:92-98. |
| APA | Huang,Yanyan,Ran,Xiang,Lin,Youhui,Ren,Jinsong,&Qu,Xiaogang.(2015).Enzyme-regulated the changes of pH values for assembling a colorimetric and multistage interconnection logic network with multiple readouts.analytica chimica acta,870,92-98. |
| MLA | Huang,Yanyan,et al."Enzyme-regulated the changes of pH values for assembling a colorimetric and multistage interconnection logic network with multiple readouts".analytica chimica acta 870(2015):92-98. |
入库方式： OAI收割
来源：长春应用化学研究所
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