Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems
文献类型：期刊论文
| 作者 | Ren,Jiangtao; Wang,Tianshu; Wang,Erkang; Wang,Jin |
| 刊名 | analyst
 |
| 出版日期 | 2015 |
| 卷号 | 140期号:8页码:2556-2572 |
| 关键词 | SPLIT G-QUADRUPLEX SWITCH-ON PROBE PARALLEL G-QUADRUPLEX CIRCLE AMPLIFIED SYNTHESIS SURFACE-PLASMON RESONANCE DNA STRAND DISPLACEMENT ION-DEPENDENT DNAZYMES POTASSIUM-ION NUCLEIC-ACID FLUORESCENCE DETECTION |
| 通讯作者 | wang,ek |
| 英文摘要 | g-quadruplex (g4), as one of the significant functional nucleic acids (fnas), has attracted researchers' wide attention, and in particular has been employed for the construction of label-free molecular sensors and logic systems based on the peroxidase-like activity of the g4-hemin complex and g4-enhanced luminescence of g4-binding organic dyes. its cation-dependent conformation and stability provide opportunities for the recognition of metal ion inputs and application of a split g4 strategy. moreover, coupling the g4 sequence with other fnas, e.g. metal ion-dependent dnazymes and aptamers, has prominently broadened the range of possible targets from metal ions and dna to diverse proteins and cells. although there are limitations, such as a low ability of anti-interference and multiplex analysis, the excellent advantages (e.g. simplicity and low cost) endow the g4-mediated strategy with tremendous potential to be further exploited for practical bioanalysis and complicated dna computing. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-31 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/65183]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Ren,Jiangtao,Wang,Tianshu,Wang,Erkang,et al. Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems[J]. analyst,2015,140(8):2556-2572. |
| APA | Ren,Jiangtao,Wang,Tianshu,Wang,Erkang,&Wang,Jin.(2015).Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems.analyst,140(8),2556-2572. |
| MLA | Ren,Jiangtao,et al."Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems".analyst 140.8(2015):2556-2572. |
入库方式： OAI收割
来源：长春应用化学研究所
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