Small molecular nanomedicines made from a camptothecin dimer containing a disulfide bond
文献类型：期刊论文
| 作者 | Pei,Qing; Hu,Xiuli; Li,Zhensheng; Xie,Zhigang; Jing,Xiabin |
| 刊名 | rsc advances
 |
| 出版日期 | 2015 |
| 卷号 | 5期号:99页码:81499-81501 |
| 关键词 | DRUG-DELIVERY CANCER-THERAPY NANOPARTICLES MICELLES PRODRUG CONJUGATE EFFICACY RELEASE |
| 通讯作者 | xie,zg |
| 英文摘要 | a small molecular camptothecin (cpt) dimer could self-assemble into stable nanoparticles in aqueous solution, which was characterized by tem and dls. these nanomedicines could be internalized by cancer cells as revealed by confocal laser scanning microscopy, and indicated high cellular proliferation inhibition toward hela and hepg2 cells with low ic50 values and reduction-responsive cytotoxicity towards hela cells. the feasible assembly method and outstanding properties of cpt-nps provide an alternative approach for exploring new nanomedicines for cancer therapy. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-31 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/67860]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Pei,Qing,Hu,Xiuli,Li,Zhensheng,et al. Small molecular nanomedicines made from a camptothecin dimer containing a disulfide bond[J]. rsc advances,2015,5(99):81499-81501. |
| APA | Pei,Qing,Hu,Xiuli,Li,Zhensheng,Xie,Zhigang,&Jing,Xiabin.(2015).Small molecular nanomedicines made from a camptothecin dimer containing a disulfide bond.rsc advances,5(99),81499-81501. |
| MLA | Pei,Qing,et al."Small molecular nanomedicines made from a camptothecin dimer containing a disulfide bond".rsc advances 5.99(2015):81499-81501. |
入库方式： OAI收割
来源：长春应用化学研究所
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