Fe2O3@Au core@shell nanoparticle-graphene nanocomposites as theranostic agents for bioimaging and chemo-photothermal synergistic therapy
文献类型：期刊论文
| 作者 | Chen,Hongbo; Liu,Fuyao; Lei,Zhen; Ma,Lina; Wang,Zhenxin |
| 刊名 | rsc advances
 |
| 出版日期 | 2015 |
| 卷号 | 5期号:103页码:84980-84987 |
| 关键词 | PHOTODYNAMIC CANCER-THERAPY DRUG-DELIVERY MAGNETIC-RESONANCE HYBRID NANOPARTICLES MESOPOROUS SILICA GOLD NANOSHELLS OXIDE TUMOR CELLS NANOMATERIALS |
| 通讯作者 | ma,ln |
| 英文摘要 | herein, we present the synthesis and application of a new type of graphene-based magnetic and plasmonic nanocomposite for magnetic-field-assisted drug delivery and chemo-photothermal synergistic therapy. the nanocomposites were prepared via conjugation of the pegylated fe2o3@au core/shell nanoparticles (fe2o3@au nps) with reduced graphene oxide (rgo). the hybrid nanostructures (rgo-fe2o3@au nps) are superparamagnetic and show great photothermal conversion efficiency under 808 nm near-infrared (nir) laser irradiation and high drug loading ability (1.0 mg mg(-1)). mtt cell viability assay demonstrates that the chemotherapeutic drug, doxorubicin loaded rgo-fe2o3@au nps (dox-rgo-fe2o3@au nps) have synergistic interaction between photothermal therapy (ptt) and chemotherapy. furthermore, in vitro studies using hela cells show that the chemo-photothermal therapeutic efficacy of dox-rgo-fe2o3@au nps can be dramatically improved by the assistance of magnetic-field-guided drug delivery. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-31 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/67862]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Chen,Hongbo,Liu,Fuyao,Lei,Zhen,et al. Fe2O3@Au core@shell nanoparticle-graphene nanocomposites as theranostic agents for bioimaging and chemo-photothermal synergistic therapy[J]. rsc advances,2015,5(103):84980-84987. |
| APA | Chen,Hongbo,Liu,Fuyao,Lei,Zhen,Ma,Lina,&Wang,Zhenxin.(2015).Fe2O3@Au core@shell nanoparticle-graphene nanocomposites as theranostic agents for bioimaging and chemo-photothermal synergistic therapy.rsc advances,5(103),84980-84987. |
| MLA | Chen,Hongbo,et al."Fe2O3@Au core@shell nanoparticle-graphene nanocomposites as theranostic agents for bioimaging and chemo-photothermal synergistic therapy".rsc advances 5.103(2015):84980-84987. |
入库方式： OAI收割
来源：长春应用化学研究所
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