Polymeric Nanocarriers for Drug Delivery in Osteosarcoma Treatment
文献类型：期刊论文
| 作者 | Gu,Xueyuan; Ding,Jianxun; Zhang,Zhiyu; Li,Qin; Zhuang,Xiuli; Chen,Xuesi |
| 刊名 | current pharmaceutical design
 |
| 出版日期 | 2015 |
| 卷号 | 21期号:36页码:5187-5197 |
| 关键词 | TUMOR VASCULAR-PERMEABILITY HIGH-GRADE OSTEOSARCOMA OF-THE-ART IN-VITRO PHOTODYNAMIC THERAPY NEOADJUVANT CHEMOTHERAPY POLYPEPTIDE MICELLES HYBRID NANOPARTICLES ANTICANCER EFFICACY CURRENT CHALLENGES |
| 通讯作者 | ding,jx |
| 英文摘要 | osteosarcoma (os) is one of the most serious malignancies along with a high incidence in children and teenagers. although the neoadjuvant chemotherapy of os has made great progress and prolongs the five-year survival rates of patients to some extent, drugs are restrained from clinical application due to the unsatisfactory efficacy and severe side effects, especially for the systemic therapy through intravenous injection. the polymeric nanoparticles as anti-cancer drug nanocarriers make os treatment more promising and effective. specifically, various polymeric nanoparticles have been developed to overcome the difficulties in targeting delivery of drugs to os tissue and/or cells through passive and/or active strategies. this review presents an overview on the development of polymeric nanoparticles for anti-cancer drug delivery in os treatment, and briefly describes the challenge and opportunity for future development. |
| 收录类别 | SCI |
| 语种 | 英语 |
| 公开日期 | 2016-05-31 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/67911]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Gu,Xueyuan,Ding,Jianxun,Zhang,Zhiyu,et al. Polymeric Nanocarriers for Drug Delivery in Osteosarcoma Treatment[J]. current pharmaceutical design,2015,21(36):5187-5197. |
| APA | Gu,Xueyuan,Ding,Jianxun,Zhang,Zhiyu,Li,Qin,Zhuang,Xiuli,&Chen,Xuesi.(2015).Polymeric Nanocarriers for Drug Delivery in Osteosarcoma Treatment.current pharmaceutical design,21(36),5187-5197. |
| MLA | Gu,Xueyuan,et al."Polymeric Nanocarriers for Drug Delivery in Osteosarcoma Treatment".current pharmaceutical design 21.36(2015):5187-5197. |
入库方式： OAI收割
来源：长春应用化学研究所
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