中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Constant-variable flip angles for hyperpolarized media MRI

文献类型:期刊论文

作者Deng, He1,2; Zhong, Jianping1; Ruan, Weiwei1; Chen, Xian1; Sun, Xianping1; Ye, Chaohui1; Liu, Maili1; Zhou, Xin1
刊名JOURNAL OF MAGNETIC RESONANCE
出版日期2016-02-01
卷号263页码:92-100
关键词Hyperpolarized MRI Constant flip angles Constant-variable flip angles Variable flip angles
英文摘要The longitudinal magnetization of hyperpolarized media, such as hyperpolarized Xe-129, He-3, etc., is nonrenewable. When the MRI data acquisition begins at the k-domain center, a constant flip angle (CFA) results in an image of high signal-to-noise ratio (SNR) but sacrifices the accuracy of spatial information. On the other hand, a variable flip angle (VFA) strategy results in high accuracy but suffers from a low SNR. In this paper, we propose a novel scheme to optimize both the SNR and accuracy, called constant-variable flip angles (CVFA). The proposed scheme suggests that hyperpolarized magnetic resonance signals are firstly acquired through a train of n* CFA excitation pulses, followed by a train of N-n* VFA excitation pulses. We simulate and optimize the flip angle used in the CFA section, the number of CFA excitation pulses, the number of VFA excitation pulses, and the initial and final variable flip angles adopted in the VFA section. Phantom and in vivo experiments demonstrate the good performance of the CVFA designs and their ability to maintain both high SNR and spatial resolution. (C) 2016 Elsevier Inc. All rights reserved.
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences ; Technology
类目[WOS]Biochemical Research Methods ; Physics, Atomic, Molecular & Chemical ; Spectroscopy
研究领域[WOS]Biochemistry & Molecular Biology ; Physics ; Spectroscopy
关键词[WOS]NOBLE-GAS MRI ; INDUCED POLARIZATION ; PARA-HYDROGEN ; LUNG ; ACQUISITION ; XE-129 ; NMR
收录类别SCI
语种英语
WOS记录号WOS:000370891700010
公开日期2016-05-31
源URL[http://ir.wipm.ac.cn/handle/112942/9234]  
专题武汉物理与数学研究所_磁共振基础研究部
作者单位1.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Natl Ctr Magnet Resonance Wuhan, Wuhan 430071, Peoples R China
2.Cent China Normal Univ, Dept Informat Technol, Wuhan 430079, Peoples R China
推荐引用方式
GB/T 7714
Deng, He,Zhong, Jianping,Ruan, Weiwei,et al. Constant-variable flip angles for hyperpolarized media MRI[J]. JOURNAL OF MAGNETIC RESONANCE,2016,263:92-100.
APA Deng, He.,Zhong, Jianping.,Ruan, Weiwei.,Chen, Xian.,Sun, Xianping.,...&Zhou, Xin.(2016).Constant-variable flip angles for hyperpolarized media MRI.JOURNAL OF MAGNETIC RESONANCE,263,92-100.
MLA Deng, He,et al."Constant-variable flip angles for hyperpolarized media MRI".JOURNAL OF MAGNETIC RESONANCE 263(2016):92-100.

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来源:武汉物理与数学研究所

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