Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii
文献类型：期刊论文
| 作者 | Sun, Zhang-Hua ; Tan, Ning-Hua ; Zeng, Guang-Zhi ; Zhang, Yu-Mei |
| 刊名 | MOLECULES
 |
| 出版日期 | 2016 |
| 卷号 | 21期号:5 |
| 关键词 | Sabina gaussenii cinnamyl isovalerate cytotoxicity |
| 中文摘要 | Chemical investigation of the 90% acetone extract of the branches and leaves of Sabina gaussenii led to the isolation of two new cinnamyl isovalerate derivatives (1-2) and eighteen known compounds (3-20). Their structures were determined mainly by means of MS, 1D- and 2D-NMR data, and this is the first time these compounds have been reported from this plant. The biological activity test results indicated that the 90% acetone extract showed cytotoxicity against the human lung adenocarcinoma (A549) cell line (IC50 = 0.98 +/- 0.1 mu g/mL), compound 6 showed cytotoxicities against human cervical carcinoma (HeLa) (IC50 = 0.4 +/- 0.1 mu M) and human gastric carcinoma (BGC-823) (IC50 = 0.9 +/- 0.2 mu M) cancer cell lines, and compound 19 showed cytotoxicities against HeLa (IC50 = 1.5 +/- 0.4 mu M), BGC-823 (IC50 = 7.0 +/- 0.8 mu M), and A549 (IC50 = 10.6 +/- 1.5 mu M) cancer cell lines. |
| 公开日期 | 2016-06-06 |
| 源URL | [http://ir.xtbg.org.cn/handle/353005/9877]  |
| 专题 | 西双版纳热带植物园_2012年后新成立研究组 |
| 推荐引用方式 GB/T 7714 | Sun, Zhang-Hua,Tan, Ning-Hua,Zeng, Guang-Zhi,et al. Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii[J]. MOLECULES,2016,21(5). |
| APA | Sun, Zhang-Hua,Tan, Ning-Hua,Zeng, Guang-Zhi,&Zhang, Yu-Mei.(2016).Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii.MOLECULES,21(5). |
| MLA | Sun, Zhang-Hua,et al."Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii".MOLECULES 21.5(2016). |
入库方式： OAI收割
来源：西双版纳热带植物园
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