中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Self-Assembled Smart Nanocarriers for Targeted Drug Delivery

文献类型:期刊论文

作者Cui, Wei1; Li, Junbai1; Decher, Gero2,3
刊名ADVANCED MATERIALS
出版日期2016-02-10
卷号28期号:6页码:1302-1311
关键词molecular assembly nanostructure drug carriers selective recognition
英文摘要Nanostructured drug-carrier systems promise numerous benefits for drug delivery. They can be engineered to precisely control drug-release rates or to target specific sites within the body with a specific amount of therapeutic agent. However, to achieve the best therapeutic effects, the systems should be designed for carrying the optimum amount of a drug to the desired target where it should be released at the optimum rate for a specified time. Despite numerous attempts, fulfilling all of these requirements in a synergistic way remains a huge challenge. The trend in drug delivery is consequently directed toward integrated multifunctional carrier systems, providing selective recognition in combination with sustained or triggered release. Capsules as vesicular systems enable drugs to be confined for controlled release. Furthermore, carriers modified with recognition groups can enhance the capability of encapsulated drug efficacy. Here, recent advances are reviewed regarding designing and preparing assembled capsules with targeting ligands or size controllable for selective recognition in drug delivery.
收录类别SCI
语种英语
源URL[http://ir.iccas.ac.cn/handle/121111/33809]  
专题化学研究所_有机固体实验室
作者单位1.Chinese Acad Sci, Inst Chem, Key Lab Colloid Interface & Chem Thermodynam, BNLMS, Beijing 100190, Peoples R China
2.Univ Strasbourg, Fac Chim, 1 Rue Blaise Pascal, F-67008 Strasbourg, France
3.Inst Charles Sadron, CNRS, 23 Rue Loess, F-67034 Strasbourg, France
推荐引用方式
GB/T 7714
Cui, Wei,Li, Junbai,Decher, Gero. Self-Assembled Smart Nanocarriers for Targeted Drug Delivery[J]. ADVANCED MATERIALS,2016,28(6):1302-1311.
APA Cui, Wei,Li, Junbai,&Decher, Gero.(2016).Self-Assembled Smart Nanocarriers for Targeted Drug Delivery.ADVANCED MATERIALS,28(6),1302-1311.
MLA Cui, Wei,et al."Self-Assembled Smart Nanocarriers for Targeted Drug Delivery".ADVANCED MATERIALS 28.6(2016):1302-1311.

入库方式: OAI收割

来源:化学研究所

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