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Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials
文献类型：期刊论文
| 作者 | Zhao F(赵峰) ; Zhao Y(赵颖); Chang XL(常雪灵); Chen CY(陈春英); Zhao YL(赵宇亮); Zhao, F; Zhao, Y; Liu, Y; Chang, XL; Chen, CY
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| 刊名 | SMALL
 |
| 出版日期 | 2011 |
| 卷号 | 7期号:10页码:1322-1337 |
| 通讯作者 | [Zhao, Feng ; Zhao, Ying ; Chang, Xueling ; Chen, Chunying ; Zhao, Yuliang] Chinese Acad Sci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Inst High Energy Phys, Beijing 100049, Peoples R China ; [Zhao, Ying ; Liu, Ying ; Chen, Chunying ; Zhao, Yuliang] Natl Ctr Nanosci & Technol China, Beijing 100190, Peoples R China |
| 英文摘要 | The interactions of nanoparticles with the soft surfaces of biological systems like cells play key roles in executing their biomedical functions and in toxicity. The discovery or design of new biomedical functions, or the prediction of the toxicological consequences of nanoparticles in vivo, first require knowledge of the interplay processes of the nanoparticles with the target cells. This article focusses on the cellular uptake, location and translocation, and any biological consequences, such as cytotoxicity, of the most widely studied and used nanoparticles, such as carbon-based nanoparticles, metallic nanoparticles, and quantum dots. The relevance of the size and shape, composition, charge, and surface chemistry of the nanoparticles in cells is considered. The intracellular uptake pathways of the nanoparticles and the cellular responses, with potential signaling pathways activated by nanoparticle interactions, are also discussed. |
| 学科主题 | Chemistry; Science & Technology - Other Topics; Materials Science; Physics |
| 类目[WOS] | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 原文出处 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000291087900004 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/239278]  |
| 专题 | 高能物理研究所_多学科研究中心 高能物理研究所_加速器中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Zhao F,Zhao Y,Chang XL,et al. Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials[J]. SMALL,2011,7(10):1322-1337. |
| APA | 赵峰.,赵颖.,常雪灵.,陈春英.,赵宇亮.,...&Zhao, YL.(2011).Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials.SMALL,7(10),1322-1337. |
| MLA | 赵峰,et al."Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials".SMALL 7.10(2011):1322-1337. |
入库方式： OAI收割
来源：高能物理研究所
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