Direct evidence for interaction between lead ions and kidney DNA from silver crucian carp
文献类型:期刊论文
作者 | Hong, FS; Wu, C; Liu, C; Wang, L![]() ![]() ![]() |
刊名 | CHEMOSPHERE
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出版日期 | 2007 |
卷号 | 68期号:8页码:1442-1446 |
关键词 | lead silver crucian carp DNA spectroscopy |
通讯作者 | Suzhou Univ, Coll Life Sci, Suzhou 215123, Peoples R China ; Suzhou Univ, Lib, Suzhou 215123, Peoples R China ; Chinese Acad Sci, Inst High Energy Phys, Synchrotron Radiat Lab, Beijing 100039, Peoples R China ; Univ Oklahoma, Dept Bot & Microbiol, Norman, OK 73019 USA |
英文摘要 | A direct interaction of lead (Pb) with kidney DNA from silver crucian carp (Carassius auratus gibelio) has been systematically studied in vitro using multi-techniques, including UV-vis absorption, extended X-ray absorption fine structure, vacuum ultraviolet circular dichroism spectral methods and gel electrophoresis. We find that Pb is bound with four oxygen or nitrogen atoms of DNA in its fresh shell at the distances of 2.64 angstrom. Additionally, Pb may bind to the oxygen atom of nucleic acid or nitrogen atom of base pairs of DNA in that obvious changes in the secondary structure of DNA are found after Pb treatment. However, this direct interaction of Pb with DNA do not cause DNA cleavage in vitro. (C) 2007 Elsevier Ltd. All rights reserved. |
学科主题 | Environmental Sciences & Ecology |
类目[WOS] | Environmental Sciences |
研究领域[WOS] | Environmental Sciences & Ecology |
原文出处 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000248076700006 |
源URL | [http://ir.ihep.ac.cn/handle/311005/239356] ![]() |
专题 | 高能物理研究所_多学科研究中心 |
作者单位 | 中国科学院高能物理研究所 |
推荐引用方式 GB/T 7714 | Hong, FS,Wu, C,Liu, C,et al. Direct evidence for interaction between lead ions and kidney DNA from silver crucian carp[J]. CHEMOSPHERE,2007,68(8):1442-1446. |
APA | Hong, FS.,Wu, C.,Liu, C.,Wang, L.,Gao, FQ.,...&谢亚宁.(2007).Direct evidence for interaction between lead ions and kidney DNA from silver crucian carp.CHEMOSPHERE,68(8),1442-1446. |
MLA | Hong, FS,et al."Direct evidence for interaction between lead ions and kidney DNA from silver crucian carp".CHEMOSPHERE 68.8(2007):1442-1446. |
入库方式: OAI收割
来源:高能物理研究所
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