Effects of acute lanthanum exposure on calcium absorption in rats
文献类型：期刊论文
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| 作者 | He X(何潇) ; Zhang ZY(张智勇); Feng LX(冯流星); Li ZJ(李子杰); Yang JH; Zhao YL(赵宇亮); Chai ZF(柴之芳); He, X; Zhang, ZY; Feng, LX
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| 刊名 | JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
 ; JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
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| 出版日期 | 2007 ; 2007 |
| 卷号 | 272期号:3页码:557-559 |
| DOI | 10.1007/s10967-007-0623-1 |
| 通讯作者 | Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China ; Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China ; Shenzhen Univ, Inst Nucl Technol, Shenzhen 518060, Peoples R China ; Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, Beijing 100049, Peoples R China ; Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China ; Shenzhen Univ, Inst Nucl Technol, Shenzhen 518060, Peoples R China |
| 文献子类 | Article |
| 英文摘要 | After an acute exposure to lanthanum chloride, the pharmacokinetics of calcium uptake in rats was studied by radioactive Ca-47 tracer. The accumulated doses of calcium in the left femurs during 24 hours were determined. The results showed that the area under the curves (AUC), specific activity of maximal blood Ca-47 concentration (C-max ), distribution rate constant (K-a) and the accumulated dose of calcium in the left femur decreased while time to C-max (T-peak) increased with the rising dosage of lanthanum exposure. It indicated that lanthanum expose had a negative effect on calcium absorption.; After an acute exposure to lanthanum chloride, the pharmacokinetics of calcium uptake in rats was studied by radioactive Ca-47 tracer. The accumulated doses of calcium in the left femurs during 24 hours were determined. The results showed that the area under the curves (AUC), specific activity of maximal blood Ca-47 concentration (C-max ), distribution rate constant (K-a) and the accumulated dose of calcium in the left femur decreased while time to C-max (T-peak) increased with the rising dosage of lanthanum exposure. It indicated that lanthanum expose had a negative effect on calcium absorption. |
| 学科主题 | Chemistry; Nuclear Science & Technology ; Chemistry; Nuclear Science & Technology |
| 类目[WOS] | Chemistry, Analytical ; Chemistry, Inorganic & Nuclear ; Nuclear Science & Technology |
| 研究领域[WOS] | Chemistry ; Nuclear Science & Technology |
| URL标识 | 查看原文 |
| WOS研究方向 | Chemistry ; Nuclear Science & Technology |
| 原文出处 | SCI |
| 语种 | 英语 ; 英语 |
| WOS记录号 | WOS:000246184200023 ; WOS:000246184200023 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/237938]  |
| 专题 | 高能物理研究所_院士 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | He X,Zhang ZY,Feng LX,et al. Effects of acute lanthanum exposure on calcium absorption in rats, Effects of acute lanthanum exposure on calcium absorption in rats[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,2007, 2007,272, 272(3):557-559, 557-559. |
| APA | 何潇.,张智勇.,冯流星.,李子杰.,Yang JH.,...&Chai, ZF.(2007).Effects of acute lanthanum exposure on calcium absorption in rats.JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY,272(3),557-559. |
| MLA | 何潇,et al."Effects of acute lanthanum exposure on calcium absorption in rats".JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY 272.3(2007):557-559. |
入库方式： OAI收割
来源：高能物理研究所
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