Comparison Study on the Antibacterial Activity of Nano- or Bulk-Cerium Oxide
文献类型：期刊论文
| 作者 | Kuang, YS; He X(何潇) ; Zhang ZY(张智勇); Li YY(李媛媛); Zhang HF(张海凤); Ma YH(马宇辉); Chai ZF(柴之芳); He, X; Zhang, ZY; Li, YY
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| 刊名 | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
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| 出版日期 | 2011 |
| 卷号 | 11期号:5页码:4103-4108 |
| 关键词 | Cerium Oxide Antibacterial Activity Particle Size |
| 通讯作者 | [He, Xiao ; Zhang, Zhiyong ; Li, Yuanyuan ; Zhang, Haifeng ; Ma, Yuhui ; Chai, Zhifang] Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Nucl Analyt Tech, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China ; [Kuang, Yashu ; Wu, Zhenqiang] S China Univ Technol, Sch Biol Sci & Engn, Guangzhou 510641, Peoples R China ; [Li, Yuanyuan ; Zhang, Haifeng] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 英文摘要 | Due to the unique physical and chemical properties, nanosized cerium oxide (n-CeO(2)) has attracted considerable interest in many fields of research. The potential, the growing use and the mass production of n-CeO(2) have stimulated research on their potential impact on the environment and human health. However, the toxicological definition for CeO(2) nanoparticles (NPs) is still quite controversial. In the present work, we evaluated the antibacterial activity of CeO(2) NPs sized ca. 7 nm (7-CeO(2)), ca. 25 nm (25-CeO(2)) and their bulk counterpart (b-CeO(2)), using gram-negative Escherichia coli (E. coli). Our results suggest that all the three types of CeO(2) particles have antibacterial activity, and both the NPs are more toxic than b-CeO(2). The rise in intracellular ROS level induced by direct contact of particles with the surface of E. coli was involved in the mechanism for the antibacterial activity of CeO(2) NPs. Exposure to 25-CeO(2) could also impair the integrity of the outer membrane within E. coli cells. Due to agglomeration and negligible effect on membrane integrity, 7-CeO(2) did riot exhibit greater antibacterial activity than 25-CeO(2). |
| 学科主题 | Chemistry; Science & Technology - Other Topics; Materials Science; Physics |
| 类目[WOS] | Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 原文出处 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000290692400050 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/239959]  |
| 专题 | 高能物理研究所_院士 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Kuang, YS,He X,Zhang ZY,et al. Comparison Study on the Antibacterial Activity of Nano- or Bulk-Cerium Oxide[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2011,11(5):4103-4108. |
| APA | Kuang, YS.,何潇.,张智勇.,李媛媛.,张海凤.,...&Chai, ZF.(2011).Comparison Study on the Antibacterial Activity of Nano- or Bulk-Cerium Oxide.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,11(5),4103-4108. |
| MLA | Kuang, YS,et al."Comparison Study on the Antibacterial Activity of Nano- or Bulk-Cerium Oxide".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 11.5(2011):4103-4108. |
入库方式： OAI收割
来源：高能物理研究所
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