Separation of three phenolic high-molecular-weight compounds from the crude extract of Terminalia Chebula Retz. by ultrasound-assisted extraction and high-speed counter-current chromatography
文献类型：期刊论文
| 作者 | Zou, Deng-lang1,2,3; Chen, Tao1,2; Li, Hong-mei1,2,3; Chen, Chen1,2; Zhao, Jing-yang1,2; Li, Yu-lin1,2 |
| 刊名 | journal of separation science
 |
| 出版日期 | 2016-04-01 |
| 卷号 | 39期号:7页码:1278-1285 |
| 关键词 | Crude extracts High-speed counter-current chromatography Phenolic compounds Response surface methodology Terminalia chebula Retz |
| 英文摘要 | this study presents an efficient strategy for separation of three phenolic compounds with high molecular weight from the crude extract of terminalia chebula retz. by ultrasound-assisted extraction and high-speed counter-current chromatography. the ultrasound-assisted extraction conditions were optimized by response surface methodology and the results showed the target compounds could be well enriched under the optimized extraction conditions. then the crude extract was directly separated by high-speed counter-current chromatography without any pretreatment using n-hexane/ethyl acetate/methanol/water (1:7:0.5:3, v/v/v/v) as the solvent system. in 180 min, 13 mg of a, 18 mg of b, and 9 mg of c were obtained from 200 mg of crude sample. their structures were identified as chebulagic acid (a, 954 da), chebulinic acid (b, 956 da), and ellagic acid (c) by h-1 nmr spectroscopy. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | response-surface methodology ; polyphenolic compounds ; preparative isolation ; alpha-glucosidase ; gallic acid ; purification ; optimization ; antioxidant ; fruits ; ultrafiltration |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000374029500009 |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/5714]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zou, Deng-lang,Chen, Tao,Li, Hong-mei,et al. Separation of three phenolic high-molecular-weight compounds from the crude extract of Terminalia Chebula Retz. by ultrasound-assisted extraction and high-speed counter-current chromatography[J]. journal of separation science,2016,39(7):1278-1285. |
| APA | Zou, Deng-lang,Chen, Tao,Li, Hong-mei,Chen, Chen,Zhao, Jing-yang,&Li, Yu-lin.(2016).Separation of three phenolic high-molecular-weight compounds from the crude extract of Terminalia Chebula Retz. by ultrasound-assisted extraction and high-speed counter-current chromatography.journal of separation science,39(7),1278-1285. |
| MLA | Zou, Deng-lang,et al."Separation of three phenolic high-molecular-weight compounds from the crude extract of Terminalia Chebula Retz. by ultrasound-assisted extraction and high-speed counter-current chromatography".journal of separation science 39.7(2016):1278-1285. |
入库方式： OAI收割
来源：西北高原生物研究所
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