Addiction: From Context-Induced Hedonia to Appetite, Based on Transition of Micro-behaviors in Morphine Abstinent Tree Shrews
文献类型：期刊论文
| 作者 | Duan, Ying1,2; Shen, Fang1 ; Gu, Tingting1,2; Sui, Nan1
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| 刊名 | FRONTIERS IN PSYCHOLOGY
 |
| 出版日期 | 2016-06-07 |
| 卷号 | 7期号:0页码:816 |
| 关键词 | tree shrews addiction morphine CPP micro-behaviors transition palatable food |
| ISSN号 | 1664-1078 |
| 英文摘要 | Drug addiction is viewed as a maladaptive memory induced by contextual cues even in the abstinent state. However, the variations of hedonia and appetite induced by the context during the abstinence have been neglected. To distinguish the representative behaviors between hedonia and appetite, micro-behaviors in abstinent animal such as psycho-activity and drug seeking behaviors were observed in morphine conditioned place preference (CPP). To confirm the different effects of reward between drug and natural reward, a palatable food CPP paradigm was compared in current work. After a 10-day training in CPP with morphine or food, the preference was tested on day 1, 14, 28, and the changes of micro-behaviors were analyzed further. Our data showed that tree shrews treated with morphine performed more jumps on day 1 and more visits to saline paired side on day 28, which indicated a featured behavioral transition from psycho-activity to seeking behavior during drug abstinence. Meanwhile, food conditioned animals only displayed obvious seeking behaviors in the three tests. The results suggest that the variations of micro-behaviors could imply such a transition from hedonic response to appetitive behaviors during morphine abstinence, which provided a potential behavioral basis for further neural mechanism studies. |
| WOS标题词 | Social Sciences |
| 类目[WOS] | Psychology, Multidisciplinary |
| 研究领域[WOS] | Psychology |
| 关键词[WOS] | CONDITIONED PLACE PREFERENCE ; GOAL-DIRECTED BEHAVIORS ; NUCLEUS-ACCUMBENS ; GLUTAMATE TRANSMISSION ; INCENTIVE SALIENCE ; COCAINE ADDICTION ; REWARD CIRCUITRY ; DRUG-ADDICTION ; NEURAL SYSTEMS ; FOOD REWARD |
| 收录类别 | SSCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000377254100001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/19942]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Duan, Ying,Shen, Fang,Gu, Tingting,et al. Addiction: From Context-Induced Hedonia to Appetite, Based on Transition of Micro-behaviors in Morphine Abstinent Tree Shrews[J]. FRONTIERS IN PSYCHOLOGY,2016,7(0):816. |
| APA | Duan, Ying,Shen, Fang,Gu, Tingting,&Sui, Nan.(2016).Addiction: From Context-Induced Hedonia to Appetite, Based on Transition of Micro-behaviors in Morphine Abstinent Tree Shrews.FRONTIERS IN PSYCHOLOGY,7(0),816. |
| MLA | Duan, Ying,et al."Addiction: From Context-Induced Hedonia to Appetite, Based on Transition of Micro-behaviors in Morphine Abstinent Tree Shrews".FRONTIERS IN PSYCHOLOGY 7.0(2016):816. |
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来源：心理研究所
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