Patients with bipolar disorder show differential executive dysfunctions: A case-control study
文献类型：期刊论文
| 作者 | Leung, Meranda M. W.1; Lui, Simon S. Y.1,2,3; Wang, Ya2 ; Tsui, Chi F.1; Au, Angie C. W.1; Yeung, Hera K. H.1; Yang, Tian-xiao2; Li, Zhi2,3; Cheng, Chi-wai1; Cheung, Eric F. C.1
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| 刊名 | PSYCHIATRY RESEARCH
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| 出版日期 | 2016-04-30 |
| 卷号 | 238期号:0页码:129-136 |
| 关键词 | Fractionation of executive function Bipolar I disorder Supervisory attention system |
| ISSN号 | 0165-1781 |
| 英文摘要 | Executive deficits in euthymic bipolar I disorder were examined in a fractionated manner based on the "Supervisory Attentional System" (SAS) model, and the relationship between the degree of executive impairment and the demographic and clinical characteristics of bipolar I participants was explored. A battery of neurocognitive tests capturing specific components of executive function was administered on 30 patients with bipolar I disorder in euthymic state, and compared with 30 healthy controls who were matched by age, gender and IQ. A differential impairment in executive function was demonstrated in euthymic bipolar I participants by using a fractionated approach of the SAS. Euthymic bipolar I patients were found to have significantly poorer performance in immediate and delayed visual memory; and in the executive domains of "initiation", "sustained attention", and "attention allocation and planning". Those with a greater number of executive impairments had lower IQ and higher negative sub-scores on PANSS. These findings might provide a the basis for further studies on identifying the executive components that are associated with particular disease characteristics of bipolar disorder, and those with poorer functional outcome, so that rehabilitation can be focused on the selective domains concerned. (C) 2016 Elsevier Ireland Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Psychiatry |
| 研究领域[WOS] | Psychiatry |
| 关键词[WOS] | I DISORDER ; EUTHYMIC PATIENTS ; NEUROCOGNITIVE IMPAIRMENT ; COGNITIVE IMPAIRMENT ; RATING-SCALE ; SCHIZOPHRENIA ; PERFORMANCE ; DEFICITS ; METAANALYSIS ; DEPRESSION |
| 收录类别 | SCI ; SSCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000375362300020 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/19990]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Leung, Meranda M. W.,Lui, Simon S. Y.,Wang, Ya,et al. Patients with bipolar disorder show differential executive dysfunctions: A case-control study[J]. PSYCHIATRY RESEARCH,2016,238(0):129-136. |
| APA | Leung, Meranda M. W..,Lui, Simon S. Y..,Wang, Ya.,Tsui, Chi F..,Au, Angie C. W..,...&Chan, Raymond C. K..(2016).Patients with bipolar disorder show differential executive dysfunctions: A case-control study.PSYCHIATRY RESEARCH,238(0),129-136. |
| MLA | Leung, Meranda M. W.,et al."Patients with bipolar disorder show differential executive dysfunctions: A case-control study".PSYCHIATRY RESEARCH 238.0(2016):129-136. |
入库方式： OAI收割
来源：心理研究所
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