中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Sheathless Separation of Particles and Cells by Viscoelastic Effects in Straight Rectangular Microchannels

文献类型:期刊论文

作者Liu C; Xue CD; Hu GQ(胡国庆)
刊名Procedia Engineering
出版日期2015
卷号126页码:721-724
关键词Viscoelasticity Particle separation Microfluidics
ISSN号1877-7058
中文摘要We demonstrate a label-free and sheathless hydrodynamic approach that successfully separate particles and cells by size in straight microchannels. Particles and cells have size-dependent stable equilibrium positions in 0.1wt % polyethylene oxide (PEO, Mw = 4脳106 g/mol) solution in a rectangular microchannel: 1渭m particles focus at the channel center while 3渭m particles focus near the channel side walls, which is completely different from the previously observed focusing at the channel center regardless of particle size. The effect of blockage ratio accounts for the deviation of large particles from the center. Utilizing this size-dependent differential migration, we successfully separate E. coli bacteria and red blood cells (RBCs) with both components tightly focused at different equilibrium positions in a straight microchannel, which has good parallelizability for higher throughput.
收录类别EI
语种英语
源URL[http://dspace.imech.ac.cn/handle/311007/59405]  
专题力学研究所_非线性力学国家重点实验室
推荐引用方式
GB/T 7714
Liu C,Xue CD,Hu GQ. Sheathless Separation of Particles and Cells by Viscoelastic Effects in Straight Rectangular Microchannels[J]. Procedia Engineering,2015,126:721-724.
APA Liu C,Xue CD,&胡国庆.(2015).Sheathless Separation of Particles and Cells by Viscoelastic Effects in Straight Rectangular Microchannels.Procedia Engineering,126,721-724.
MLA Liu C,et al."Sheathless Separation of Particles and Cells by Viscoelastic Effects in Straight Rectangular Microchannels".Procedia Engineering 126(2015):721-724.

入库方式: OAI收割

来源:力学研究所

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