Binding affinity analysis of the interaction between Homer EVH domain and ryanodine receptor with biosensors based on imaging ellipsometry
文献类型：期刊论文
| 作者 | Kang TF(康腾飞) ; Zhang KM; Yin CC; Niu Y(牛宇); Jin G(靳刚); Niu, Y; Niu, Y
|
| 刊名 | ANALYTICAL METHODS
 |
| 出版日期 | 2016 |
| 卷号 | 8期号:14页码:2936-2940 |
| 通讯作者邮箱 | gajin@imech.ac.cn |
| ISSN号 | 1759-9660 |
| 产权排序 | [Kang, Tengfei; Niu, Yu; Jin, Gang] Chinese Acad Sci, Inst Mech, NML, 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China; [Kang, Tengfei; Niu, Yu; Jin, Gang] Chinese Acad Sci, Beijing Key Lab Engn Construct & Mechanobiol, Inst Mech, 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China; [Kang, Tengfei] Univ Chinese Acad Sci, 19 Yu Quan Rd, Beijing 100049, Peoples R China; [Zhang, Kaiming; Yin, Changcheng] Peking Univ, Peking Univ Hlth Sci Ctr, Dept Biophys, Beijing 100191, Peoples R China |
| 通讯作者 | Niu, Y ; Jin, G (reprint author), Chinese Acad Sci, Inst Mech, NML, 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China. ; Niu, Y ; Jin, G (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mechanobiol, Inst Mech, 15 Bei Si Huan West Rd, Beijing 100190, Peoples R China. |
| 中文摘要 | The interaction between the Homer EVH domain and RyR plays an important role in calcium signaling channels in the heart and the skeletal muscles. A biosensor based on imaging ellipsometry was used to analyze the binding affinity between the Homer EVH domain and RyR. The results confirm that the Homer EVH domain can recognize RyR specifically with high binding affinity of approximately 10(-8) M. This information will contribute to understanding of the role of the interaction between the Homer EVH domain and RyR in intracellular calcium channels. |
| 分类号 | 二类 |
| 类目[WOS] | Chemistry, Analytical ; Food Science & Technology ; Spectroscopy |
| 研究领域[WOS] | Chemistry ; Food Science & Technology ; Spectroscopy |
| 收录类别 | SCI ; EI |
| 原文出处 | http://dx.doi.org/10.1039/c6ay00089d |
| 语种 | 英语 |
| WOS记录号 | WOS:000373440600010 |
| 源URL | [http://dspace.imech.ac.cn/handle/311007/59521]  |
| 专题 | 力学研究所_国家微重力实验室 |
| 通讯作者 | Niu, Y; Niu, Y |
| 推荐引用方式 GB/T 7714 | Kang TF,Zhang KM,Yin CC,et al. Binding affinity analysis of the interaction between Homer EVH domain and ryanodine receptor with biosensors based on imaging ellipsometry[J]. ANALYTICAL METHODS,2016,8(14):2936-2940. |
| APA | 康腾飞.,Zhang KM.,Yin CC.,牛宇.,靳刚.,...&Niu, Y.(2016).Binding affinity analysis of the interaction between Homer EVH domain and ryanodine receptor with biosensors based on imaging ellipsometry.ANALYTICAL METHODS,8(14),2936-2940. |
| MLA | 康腾飞,et al."Binding affinity analysis of the interaction between Homer EVH domain and ryanodine receptor with biosensors based on imaging ellipsometry".ANALYTICAL METHODS 8.14(2016):2936-2940. |
入库方式： OAI收割
来源：力学研究所
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