Synthesis of chiral 1,3-bis(1-(diarylphosphoryl)ethyl)-benzenes via Ir-catalyzed double asymmetric hydrogenation of bis(diarylvinylphosphine oxides)
文献类型：期刊论文
| 作者 | Liu X(刘旭); Han ZB(韩召斌); Wang Z(王正); Ding KL(丁奎岭) |
| 刊名 | Sci. China-Chem.
 |
| 出版日期 | 2014 |
| 卷号 | 57期号:8页码:1073-1078 |
| 其他题名 | 铱催化双芳基烯基膦氧类化合物的两次不对称氢化合成手性1,3-二(1-双芳基膦)-乙基苯 |
| 通讯作者 | 丁奎岭 |
| 英文摘要 | A class of chiral 1,3-bis(diarylphosphinoethyl)benzenes, which are key intermediates for the synthesis of PCP-type chiral pincer ligands, were prepared in high diastereomeric ratios and excellent ee values via double asymmetric hydrogenation of the corresponding bis(diarylvinylphosphine oxide) substrates using a SpinPhox/Ir(I) complex as the catalyst. The hydrogenation product 5a was readily transformed into the corresponding borane-protected chiral PCP-type pincer ligand 7a with high enantiomeric excess, exemplifying a viable synthetic route to optically active chiral PCP pincer ligands. |
| 学科主题 | 金属有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1007/s11426-014-5134-7 |
| 语种 | 英语 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/39087]  |
| 专题 | 上海有机化学研究所_金属有机化学国家重点实验室 |
| 作者单位 | 中科院上海有机化学研究所 |
| 推荐引用方式 GB/T 7714 | Liu X,Han ZB,Wang Z,et al. Synthesis of chiral 1,3-bis(1-(diarylphosphoryl)ethyl)-benzenes via Ir-catalyzed double asymmetric hydrogenation of bis(diarylvinylphosphine oxides)[J]. Sci. China-Chem.,2014,57(8):1073-1078. |
| APA | 刘旭,韩召斌,王正,&丁奎岭.(2014).Synthesis of chiral 1,3-bis(1-(diarylphosphoryl)ethyl)-benzenes via Ir-catalyzed double asymmetric hydrogenation of bis(diarylvinylphosphine oxides).Sci. China-Chem.,57(8),1073-1078. |
| MLA | 刘旭,et al."Synthesis of chiral 1,3-bis(1-(diarylphosphoryl)ethyl)-benzenes via Ir-catalyzed double asymmetric hydrogenation of bis(diarylvinylphosphine oxides)".Sci. China-Chem. 57.8(2014):1073-1078. |
入库方式： OAI收割
来源：上海有机化学研究所
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