Copper-catalyzed coupling of aryl iodides and tert-butyl beta-keto esters: efficient access to alpha-aryl ketones and alpha-arylacetic acid tert-butyl esters
文献类型：期刊论文
| 作者 | Zhao D(赵铎); Jiang YW(蒋咏文); Ma DW(马大为) |
| 刊名 | Tetrahedron
 |
| 出版日期 | 2014 |
| 卷号 | 70期号:20页码:3327-3332 |
| 其他题名 | 铜催化的芳基碘代物与 b-酮基叔丁酯的偶联反应: 有效合成a-芳基酮和a-芳基乙酸叔丁酯 |
| 通讯作者 | 马大为 |
| 英文摘要 | CuI/trans-4-hydroxy-t-proline catalyzed coupling of aryl iodides with tert-butyl beta-keto esters proceeded smoothly at 40 degrees C in DMF, providing alpha-aryl ketones after acid-promoted deprotection and decarboxylation of tert-butyl ester group. While CuI/2-picolinic acid catalyzed coupling of aryl iodides with tert-butyl acetoacetate at 70 degrees C in dioxane delivered alpha-arylacetic acid tert-butyl esters upon spontaneous deacylation. A wide range of functional groups, such as acetyl, methoxy, nitrile, nitro, bromo, and chloro were compatible with the reaction conditions. (C) 2013 Elsevier Ltd. All rights reserved. |
| 学科主题 | 生命有机化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1016/j.tet2013.10.017 |
| 语种 | 英语 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/38944]  |
| 专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
| 作者单位 | 中科院上海有机化学研究所 |
| 推荐引用方式 GB/T 7714 | Zhao D,Jiang YW,Ma DW. Copper-catalyzed coupling of aryl iodides and tert-butyl beta-keto esters: efficient access to alpha-aryl ketones and alpha-arylacetic acid tert-butyl esters[J]. Tetrahedron,2014,70(20):3327-3332. |
| APA | 赵铎,蒋咏文,&马大为.(2014).Copper-catalyzed coupling of aryl iodides and tert-butyl beta-keto esters: efficient access to alpha-aryl ketones and alpha-arylacetic acid tert-butyl esters.Tetrahedron,70(20),3327-3332. |
| MLA | 赵铎,et al."Copper-catalyzed coupling of aryl iodides and tert-butyl beta-keto esters: efficient access to alpha-aryl ketones and alpha-arylacetic acid tert-butyl esters".Tetrahedron 70.20(2014):3327-3332. |
入库方式： OAI收割
来源：上海有机化学研究所
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