Nickel-Catalyzed alpha-Arylation of Zinc Enolates with Polyfluoroarenes via C-F Bond Activation under Neutral Conditions
文献类型：期刊论文
| 作者 | Yu DH(于道鸿)1; Wang CS(王昌盛)1; Yao C(姚成)1; Shen QL(沈其龙)1; Lv L(吕龙)1 |
| 刊名 | Org. Lett.
 |
| 出版日期 | 2014 |
| 卷号 | 16期号:21页码:5544-5547 |
| 其他题名 | 镍催化的中性条件下锌试剂与多氟芳烃经碳氟键活化的偶联反应研究 |
| 通讯作者 | 沈其龙 ; 吕龙 |
| 英文摘要 | The first nickel-catalyzed alpha-arylation of 2-(polyfluorophenyl) pyridine with zinc enolates of esters or amides via C-F bond activation under neutral conditions is described. A variety of functional groups such as ester, amide, ether, and amine were tolerated. This method provides a simple and useful tool to synthesize fluorinated a-aryl carboxylic acids and a-aryl amides that are important intermediates for drug discovery |
| 学科主题 | 氟化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/ol502499q |
| 语种 | 英语 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/38859]  |
| 专题 | 上海有机化学研究所_中科院有机氟化学重点实验室 |
| 作者单位 | 1.中科院上海有机化学研究所 2.南京工业大学 |
| 推荐引用方式 GB/T 7714 | Yu DH,Wang CS,Yao C,et al. Nickel-Catalyzed alpha-Arylation of Zinc Enolates with Polyfluoroarenes via C-F Bond Activation under Neutral Conditions[J]. Org. Lett.,2014,16(21):5544-5547. |
| APA | 于道鸿,王昌盛,姚成,沈其龙,&吕龙.(2014).Nickel-Catalyzed alpha-Arylation of Zinc Enolates with Polyfluoroarenes via C-F Bond Activation under Neutral Conditions.Org. Lett.,16(21),5544-5547. |
| MLA | 于道鸿,et al."Nickel-Catalyzed alpha-Arylation of Zinc Enolates with Polyfluoroarenes via C-F Bond Activation under Neutral Conditions".Org. Lett. 16.21(2014):5544-5547. |
入库方式： OAI收割
来源：上海有机化学研究所
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