Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes
文献类型：期刊论文
| 作者 | Xiao YL(肖玉兰); Zhang B(章博); Feng Z(冯璋); Zhang XG(张新刚) |
| 刊名 | Org. Lett.
 |
| 出版日期 | 2014 |
| 卷号 | 16期号:18页码:4822-4825 |
| 其他题名 | 一种简便合成芳基(杂芳基)二氟甲烷的方法: 有机硼的杂芳基二氟甲基化 |
| 通讯作者 | 张新刚 |
| 英文摘要 | A first example of Pd-catalyzed heteroaryldifluoromethylation of organoborons with bromodifluoromethylated heteroarenes has been described. The use of phosphine ligand PAd(2)(n-Bu)center dot HI is critical for the reaction efficiency. With use of this ligand, a wide range of aryl(heteroaryl)difluoromethanes were obtained with high efficiency. The notable features of this reaction are its broad substrate scope and excellent functional group compatibility, thus providing a facile protocol for application in drug discovery and development. |
| 学科主题 | 氟化学 |
| 收录类别 | SCI |
| 原文出处 | http://dx.doi.org/10.1021/ol502121m |
| 语种 | 英语 |
| 源URL | [http://ir.sioc.ac.cn/handle/331003/38881]  |
| 专题 | 上海有机化学研究所_中科院有机氟化学重点实验室 |
| 作者单位 | 中科院上海有机化学研究所 |
| 推荐引用方式 GB/T 7714 | Xiao YL,Zhang B,Feng Z,et al. Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes[J]. Org. Lett.,2014,16(18):4822-4825. |
| APA | 肖玉兰,章博,冯璋,&张新刚.(2014).Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes.Org. Lett.,16(18),4822-4825. |
| MLA | 肖玉兰,et al."Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes".Org. Lett. 16.18(2014):4822-4825. |
入库方式： OAI收割
来源：上海有机化学研究所
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