Fast Determination of Flip Angle and T-1 in Hyperpolarized Gas MRI During a Single Breath-Hold
文献类型：期刊论文
| 作者 | Zhong, Jianping1,2; Ruan, Weiwei1; Han, Yeqing1; Sun, Xianping1; Ye, Chaohui1,2; Zhou, Xin1 |
| 刊名 | SCIENTIFIC REPORTS
 |
| 出版日期 | 2016-05-12 |
| 卷号 | 6 |
| 英文摘要 | MRI of hyperpolarized media, such as Xe-129 and He-3, shows great potential for clinical applications. The optimal use of the available spin polarization requires accurate flip angle calibrations and T-1 measurements. Traditional flip angle calibration methods are time-consuming and suffer from polarization losses during T-1 relaxation. In this paper, we propose a method to simultaneously calibrate flip angles and measure T-1 in vivo during a breath-hold time of less than 4 seconds. We demonstrate the accuracy, robustness and repeatability of this method and contrast it with traditional methods. By measuring the T-1 of hyperpolarized gas, the oxygen pressure in vivo can be calibrated during the same breath hold. The results of the calibration have been applied in variable flip angle (VFA) scheme to obtain a stable steady-state transverse magnetization. Coupled with this method, the ultra-short TE (UTE) and constant VFA (CVFA) schemes are expected to give rise to new applications of hyperpolarized media. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | HE-3 MRI ; NOBLE-GASES ; IN-VIVO ; LUNG ; XE-129 ; RELAXATION ; NMR ; VENTILATION ; CALIBRATION ; DYNAMICS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000375644800001 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/9336]  |
| 专题 | 武汉物理与数学研究所_磁共振应用研究部 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Magnet Resonance Biol Syst, State Key Lab Magnet Resonance & Atom & Mol Phys, Natl Ctr Magnet Resonance Wuhan,Wuhan Inst Phys &, Wuhan 430071, Peoples R China 2.Huazhong Univ Sci & Technol, Sch Phys, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhong, Jianping,Ruan, Weiwei,Han, Yeqing,et al. Fast Determination of Flip Angle and T-1 in Hyperpolarized Gas MRI During a Single Breath-Hold[J]. SCIENTIFIC REPORTS,2016,6. |
| APA | Zhong, Jianping,Ruan, Weiwei,Han, Yeqing,Sun, Xianping,Ye, Chaohui,&Zhou, Xin.(2016).Fast Determination of Flip Angle and T-1 in Hyperpolarized Gas MRI During a Single Breath-Hold.SCIENTIFIC REPORTS,6. |
| MLA | Zhong, Jianping,et al."Fast Determination of Flip Angle and T-1 in Hyperpolarized Gas MRI During a Single Breath-Hold".SCIENTIFIC REPORTS 6(2016). |
入库方式： OAI收割
来源：武汉物理与数学研究所
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