RestrictionDigest: A powerful Perl module for simulating genomic restriction digests
文献类型：期刊论文
| 作者 | Wang, Jinpeng1,2,3,5 ; Li, Li1,4,5; Qi, Haigang1,3,5; Dua, Xuedi1,3,5; Zhang, Guofan1,3,5
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| 刊名 | ELECTRONIC JOURNAL OF BIOTECHNOLOGY
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| 出版日期 | 2016-05-01 |
| 卷号 | 21页码:36-42 |
| 关键词 | Genotyping Reduced-representation libraries Reduced-representation sequencing |
| 英文摘要 | Background: Reduced-representation sequencing technology is widely used in genotyping for its economical and efficient features. A popular way to construct the reduced-representation sequencing libraries is to digest the genomic DNA with restriction enzymes. A key factor of this method is to determine the restriction enzyme(s). But there are few computer programs which can evaluate the usability of restriction enzymes in reduced-representation sequencing. SimRAD is an R package which can simulate the digestion of DNA sequence by restriction enzymes and return enzyme loci number as well as fragment number. But for linkage mapping analysis, enzyme loci distribution is also an important factor to evaluate the enzyme. For phylogenetic studies, comparison of the enzyme performance across multiple genomes is important. It is strongly needed to develop a simulation tool to implement these functions. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000376595900005 |
| 版本 | 出版稿 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/131085]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 3.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266071, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries & Aquaculture, Qingdao 266071, Peoples R China 5.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jinpeng,Li, Li,Qi, Haigang,et al. RestrictionDigest: A powerful Perl module for simulating genomic restriction digests[J]. ELECTRONIC JOURNAL OF BIOTECHNOLOGY,2016,21:36-42. |
| APA | Wang, Jinpeng,Li, Li,Qi, Haigang,Dua, Xuedi,&Zhang, Guofan.(2016).RestrictionDigest: A powerful Perl module for simulating genomic restriction digests.ELECTRONIC JOURNAL OF BIOTECHNOLOGY,21,36-42. |
| MLA | Wang, Jinpeng,et al."RestrictionDigest: A powerful Perl module for simulating genomic restriction digests".ELECTRONIC JOURNAL OF BIOTECHNOLOGY 21(2016):36-42. |
入库方式： OAI收割
来源：海洋研究所
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