Increased activity in frontal motor cortex compensates impaired speech perception in older adults
文献类型：期刊论文
| 作者 | Du, Yi1,2 ; Buchsbaum, Bradley R.1,3; Grady, Cheryl L.1,3; Alain, Claude1,3
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| 刊名 | Nature Communications
 |
| 出版日期 | 2016-08-01 |
| 卷号 | 7期号:0页码:1-12 |
| 通讯作者邮箱 | duyi@psych.ac.cn |
| ISSN号 | 2041-1723 |
| 通讯作者 | Du, Yi ; Alain, Claude |
| 英文摘要 | Understanding speech in noisy environments is challenging, especially for seniors. Although evidence suggests that older adults increasingly recruit prefrontal cortices to offset reduced periphery and central auditory processing, the brain mechanisms underlying such compensation remain elusive. Here we show that relative to young adults, older adults show higher activation of frontal speech motor areas as measured by functional MRI during a syllable identification task at varying signal-to-noise ratios. This increased activity correlates with improved speech discrimination performance in older adults. Multivoxel pattern classification reveals that despite an overall phoneme dedifferentiation, older adults show greater specificity of phoneme representations in frontal articulatory regions than auditory regions. Moreover, older adults with stronger frontal activity have higher phoneme specificity in frontal and auditory regions. Thus, preserved phoneme specificity and upregulation of activity in speech motor regions provide a means of compensation in older adults for decoding impoverished speech representations in adverse listening conditions. |
| WOS标题词 | Science & Technology |
| 学科主题 | 老年心理学 |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | AGE-RELATED-CHANGES ; AUDITORY-CORTEX ; NOISE ; RECOGNITION ; REPRESENTATIONS ; ORGANIZATION ; MEMORY ; DEDIFFERENTIATION ; CONNECTIVITY ; PERFORMANCE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000380855800001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/20332]  |
| 专题 | 心理研究所_认知与发展心理学研究室 |
| 作者单位 | 1.Baycrest Ctr Geriatr Care, Rotman Res Inst, Toronto, ON M6A 2E1, Canada 2.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China 3.Univ Toronto, Dept Psychol, Toronto, ON M8V 2S4, Canada |
| 推荐引用方式 GB/T 7714 | Du, Yi,Buchsbaum, Bradley R.,Grady, Cheryl L.,et al. Increased activity in frontal motor cortex compensates impaired speech perception in older adults[J]. Nature Communications,2016,7(0):1-12. |
| APA | Du, Yi,Buchsbaum, Bradley R.,Grady, Cheryl L.,&Alain, Claude.(2016).Increased activity in frontal motor cortex compensates impaired speech perception in older adults.Nature Communications,7(0),1-12. |
| MLA | Du, Yi,et al."Increased activity in frontal motor cortex compensates impaired speech perception in older adults".Nature Communications 7.0(2016):1-12. |
入库方式： OAI收割
来源：心理研究所
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