Design, synthesis and evaluation of novel F-19 magnetic resonance sensitive protein tyrosine phosphatase inhibitors
文献类型：期刊论文
| 作者 | Li, Yu1; Xia, Guiquan1; Guo, Qi1; Wu, Li2; Chen, Shizhen3; Yang, Zhigang1; Wang, Wei1; Zhang, Zhong-Yin2; Zhou, Xin3; Jiang, Zhong-Xing1,3,4,5 |
| 刊名 | MEDCHEMCOMM
 |
| 出版日期 | 2016 |
| 卷号 | 7期号:8页码:1672-1680 |
| 英文摘要 | Fluorine is a highly attractive element for both medicinal chemistry and imaging technologies. To facilitate protein tyrosine phosphatase (PTP)-targeted drug discovery and imaging-guided PTP research on fluorine, several highly potent and F-19 MR sensitive PTP inhibitors were discovered through a structure-based focused library strategy. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemistry & Molecular Biology ; Chemistry, Medicinal |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 关键词[WOS] | SMALL-MOLECULE INHIBITOR ; AUTOIMMUNE-DISEASES ; IMAGING AGENT ; MRI ; DISCOVERY ; CELLS ; SHP2 ; LYP |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000381413300020 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/9500]  |
| 专题 | 武汉物理与数学研究所_磁共振应用研究部 |
| 作者单位 | 1.Wuhan Univ, Sch Pharmaceut Sci, Wuhan 430071, Peoples R China 2.Purdue Univ, Dept Med Chem & Mol Pharmacol, Ctr Canc Res, W Lafayette, IN 47907 USA 3.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Synthet Chem Nat Subst, Shanghai 200032, Peoples R China 5.Donghua Univ, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yu,Xia, Guiquan,Guo, Qi,et al. Design, synthesis and evaluation of novel F-19 magnetic resonance sensitive protein tyrosine phosphatase inhibitors[J]. MEDCHEMCOMM,2016,7(8):1672-1680. |
| APA | Li, Yu.,Xia, Guiquan.,Guo, Qi.,Wu, Li.,Chen, Shizhen.,...&Jiang, Zhong-Xing.(2016).Design, synthesis and evaluation of novel F-19 magnetic resonance sensitive protein tyrosine phosphatase inhibitors.MEDCHEMCOMM,7(8),1672-1680. |
| MLA | Li, Yu,et al."Design, synthesis and evaluation of novel F-19 magnetic resonance sensitive protein tyrosine phosphatase inhibitors".MEDCHEMCOMM 7.8(2016):1672-1680. |
入库方式： OAI收割
来源：武汉物理与数学研究所
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