Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea
文献类型：期刊论文
| 作者 | Ding, Jian-Hai1,2,3; Li, Zheng-Hui1; Wei, Kun3; Dong, Ze-Jun3 ; Ding, Zhi-Hui3; Feng, Tao1; Liu, Ji-Kai1
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2016-01-02 |
| 卷号 | 18期号:1页码:46-50 |
| 关键词 | cytotoxicities trefoliols B and C 11 beta-HSD Tremella foliacea |
| 英文摘要 | Two new sesquiterpenoids, trefoliol B (1) and trefoliol C (2), together with known echinocidin A (3), were isolated from cultures of the basidiomycetes Tremella foliacea. The new structures were elucidated on the basis of extensive spectroscopic methods. At the same time, trefoliol B (1) and echinocidin A (3) were tested for their cytotoxicities against five human cancer cell lines and for their inhibitory activities against isozymes of 11 beta-hydroxysteroid dehydrogenases (11 beta-HSD). No compound showed significant activity (IC50 > 40 mu M). Compound 1 showed moderate inhibitory activities against 11 beta-HSD1 (human IC50=13.1 mu M; mouse IC50=91.8 mu M). |
| 类目[WOS] | Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000371017700007 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/25999]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China 2.Ningxia Normal Univ, Sch Chem & Chem Engn, Guyuan 756000, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ding, Jian-Hai,Li, Zheng-Hui,Wei, Kun,et al. Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2016,18(1):46-50. |
| APA | Ding, Jian-Hai.,Li, Zheng-Hui.,Wei, Kun.,Dong, Ze-Jun.,Ding, Zhi-Hui.,...&Liu, Ji-Kai.(2016).Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,18(1),46-50. |
| MLA | Ding, Jian-Hai,et al."Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 18.1(2016):46-50. |
入库方式： OAI收割
来源：昆明植物研究所
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