Collective formal synthesis of (+/-)-rhynchophylline and homologues
文献类型：期刊论文
| 作者 | Xu, Jun1 ; Shao, Li-Dong1; Shi, Xin1,2; Ren, Jian1,2; Xia, Chengfeng1; Zhao, Qin-Shi1
|
| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2016 |
| 卷号 | 6期号:68页码:63131-63135 |
| 英文摘要 | A collective formal synthesis approach to bioactive oxindole alkaloids, including (+/-)-rhynchophylline, (+/-)-isorhynchophylline, (+/-)-mitraphylline, (+/-)-formosanine, (+/-)-isomitraphylline, and (+/-)-isoformosanine, is completed in a protecting-group free manner. Besides multigram-scaled operations, the notable feature of the synthesis is the application of two one-pot, sequential transformations. Namely, two key tetracyclic intermediates pyridinium salt 9 and monoester 14 were prepared by a one-pot N-alkylation/cross-dehydrogenative coupling sequence and a one-pot Michael/Karpocho sequence with minimal purification, respectively. |
| 类目[WOS] | Chemistry, Multidisciplinary |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | OXINDOLE ALKALOIDS ; ALZHEIMERS-DISEASE ; ISORHYNCHOPHYLLINE ; RHYNCHOPHYLLINE ; 3-SPIROOXINDOLE ; DERIVATIVES ; EPHA4 ; ACID |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000379493900004 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/28465]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Jun,Shao, Li-Dong,Shi, Xin,et al. Collective formal synthesis of (+/-)-rhynchophylline and homologues[J]. RSC ADVANCES,2016,6(68):63131-63135. |
| APA | Xu, Jun,Shao, Li-Dong,Shi, Xin,Ren, Jian,Xia, Chengfeng,&Zhao, Qin-Shi.(2016).Collective formal synthesis of (+/-)-rhynchophylline and homologues.RSC ADVANCES,6(68),63131-63135. |
| MLA | Xu, Jun,et al."Collective formal synthesis of (+/-)-rhynchophylline and homologues".RSC ADVANCES 6.68(2016):63131-63135. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。