Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens
文献类型：期刊论文
| 作者 | He, Kang; Geng, Chang-An ; Cao, Tuan-Wu; Wang, Hong-Ling; Ma, Yun-Bao; Zhang, Xue-Mei; Chen, Ji-Jun
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| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| 出版日期 | 2016 |
| 卷号 | 18期号:6页码:528-534 |
| 关键词 | Swertia patens secoiridoids swerpatic acid swerpalactone anti-HBV activity |
| 英文摘要 | Two new secoiridoids, swerpatic acid (1) with an unusual C-8 skeleton and swerpalactone (2), were isolated along with ten known compounds (3-12) from the whole plants of Swertia patens. Their structures were elucidated by comprehensive spectroscopic analyses. Eight compounds were evaluated for their anti-hepatitis B virus (HBV) activities on Hep G 2.2.15 cell line in vitro. Compounds 4 and 10 showed moderate inhibitory activities on the secretion of HBsAg with IC50 values of 1.96 and 0.50 mM. |
| 类目[WOS] | Plant Sciences ; Chemistry, Applied ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | MILEENSIS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000379666400003 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/28476]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Kang,Geng, Chang-An,Cao, Tuan-Wu,et al. Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2016,18(6):528-534. |
| APA | He, Kang.,Geng, Chang-An.,Cao, Tuan-Wu.,Wang, Hong-Ling.,Ma, Yun-Bao.,...&Chen, Ji-Jun.(2016).Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,18(6),528-534. |
| MLA | He, Kang,et al."Two new secoiridoids and other anti-hepatitis B virus active constituents from Swertia patens".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 18.6(2016):528-534. |
入库方式： OAI收割
来源：昆明植物研究所
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