中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
neo-Clerodanes from the aerial parts of Salvia leucantha

文献类型:期刊论文

作者Jiang, Yong-Jun; Su, Jia; Shi, Xin; Wu, Xing-De; Chen, Xuan-Qin; He, Juan; Shao, Li-Dong; Li, Xiao-Nian; Peng, Li-Yan; Li, Rong-Tao
刊名TETRAHEDRON
出版日期2016-09-01
卷号72期号:35页码:5507-5514
关键词neo-Clerodanes Salvia leucantha Cytotoxicity Heat shock protein 90 inhibitor Acetyl cholinesterase inhibitory activity
英文摘要Ten new neo-clerodane derivatives (1-10) and 10 known diterpenoids were identified from the aerial parts of Salvia leucantha. The structures of 1-10 were established by 1D and 2D NMR spectroscopic data analysis. The absolute configurations of 1, 3, 6, and 7 were determined by X-ray diffraction data. Compound 16 exhibited cytotoxicity against HCT116, BT474, and HepG2 cancer cell lines and was identified as a heat shock protein 90 inhibitor. Compounds 8, 15, and 16 exhibited moderate acetyl cholinesterase inhibitory activity.(C) 2016 Elsevier Ltd. All rights reserved.
类目[WOS]Chemistry, Organic
研究领域[WOS]Chemistry
关键词[WOS]REARRANGED NEOCLERODANE SKELETON ; DITERPENOIDS ; CAV ; SALVIFARICIN ; FARINACEA ; ORIGIN ; ASSAY
收录类别SCI
语种英语
WOS记录号WOS:000381530900031
源URL[http://ir.kib.ac.cn/handle/151853/28583]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
推荐引用方式
GB/T 7714
Jiang, Yong-Jun,Su, Jia,Shi, Xin,et al. neo-Clerodanes from the aerial parts of Salvia leucantha[J]. TETRAHEDRON,2016,72(35):5507-5514.
APA Jiang, Yong-Jun.,Su, Jia.,Shi, Xin.,Wu, Xing-De.,Chen, Xuan-Qin.,...&Zhao, Qin-Shi.(2016).neo-Clerodanes from the aerial parts of Salvia leucantha.TETRAHEDRON,72(35),5507-5514.
MLA Jiang, Yong-Jun,et al."neo-Clerodanes from the aerial parts of Salvia leucantha".TETRAHEDRON 72.35(2016):5507-5514.

入库方式: OAI收割

来源:昆明植物研究所

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