Induced Production of New Diterpenoids in the Fungus Penicillium funiculosum
文献类型：期刊论文
| 作者 | Liu, Dong-Ze1; Liang, Bo-Wen2; Li, Xiao-Fei2; Liu, Qiang2 |
| 刊名 | NATURAL PRODUCT COMMUNICATIONS
 |
| 出版日期 | 2014-05-01 |
| 卷号 | 9期号:5页码:607-608 |
| 关键词 | Diterpenoids Penicillium funiculosum Epigenetic modifier Biosynthesis |
| 英文摘要 | The supplementation of a DNA methyltransferase inhibitor, 5-azacytidine (5-AZ), to the culture medium of Penicillium funiculosum, dramatically altered its metabolic profiles. Analysis of the culture broth extract led to the isolation of two new prenyleudesmane diterpenoids (1-2). The isolated compounds were further evaluated for their cytotoxic and antibacterial activities. Our findings confirmed that the use of chemical epigenetic modifiers is an effective technique for promoting the expression of silent biosynthetic pathways to produce unique secondary metabolites. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Chemistry, Medicinal ; Food Science & Technology |
| 研究领域[WOS] | Pharmacology & Pharmacy ; Food Science & Technology |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000336512700002 |
| 源URL | [http://124.16.173.210/handle/834782/1403]  |
| 专题 | 天津工业生物技术研究所_发酵过程 姜文侠_期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin 300308, Peoples R China 2.Northeast Agr Univ, Harbin 150030, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Dong-Ze,Liang, Bo-Wen,Li, Xiao-Fei,et al. Induced Production of New Diterpenoids in the Fungus Penicillium funiculosum[J]. NATURAL PRODUCT COMMUNICATIONS,2014,9(5):607-608. |
| APA | Liu, Dong-Ze,Liang, Bo-Wen,Li, Xiao-Fei,&Liu, Qiang.(2014).Induced Production of New Diterpenoids in the Fungus Penicillium funiculosum.NATURAL PRODUCT COMMUNICATIONS,9(5),607-608. |
| MLA | Liu, Dong-Ze,et al."Induced Production of New Diterpenoids in the Fungus Penicillium funiculosum".NATURAL PRODUCT COMMUNICATIONS 9.5(2014):607-608. |
入库方式： OAI收割
来源：天津工业生物技术研究所
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