HGPGD: The Human Gene Population Genetic Difference Database
文献类型：期刊论文
| 作者 | Jiang, Yongshuai1; Zhang, Ruijie1; Lv, Hongchao1; Li, Jin1; Wang, Miao1; Chang, Yiman1; Lv, Wenhua1; Sheng, Xin2; Zhang, Jingjing3; Liu, Panpan1 |
| 刊名 | PLOS ONE
 |
| 出版日期 | 2013-05-22 |
| 卷号 | 8期号:5 |
| 英文摘要 | Demographic events such as migration, and evolutionary events like mutation and recombination, have contributed to the genetic variations that are found in the human genome. During the evolution and differentiation of human populations, different functional genes and pathways (a group of genes that act together to perform specific biological tasks) would have displayed different degrees of genetic diversity or evolutionary conservatism. To query the genetic differences of functional genes or pathways in populations, we have developed the human gene population genetic difference (HGPGD) database. Currently, 11 common population genetic features, 18,158 single human genes, 220 KEGG (Kyoto Encyclopedia of Genes and Genomes) human pathways and 4,639 Gene Ontology (GO) categories (3,269 in biological process; 862 in molecular function; and 508 in cellular component) are available in the HGPGD database. The 11 population genetic features are related mainly to three aspects: allele frequency, linkage disequilibrium pattern, and transferability of tagSNPs. By entering a list of Gene IDs, KEGG pathway IDs or GO category IDs and selecting a population genetic feature, users can search the genetic differences between pairwise HapMap populations. We hope that, when the researchers carry out gene-based, KEGG pathway-based or GO category-based research, they can take full account of the genetic differences between populations. The HGPGD database (V1.0) is available at http://www.bioapp.org/hgpgd. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | GENOME-WIDE ASSOCIATION ; KYOTO ENCYCLOPEDIA ; LINKAGE DISEQUILIBRIUM ; PATHWAY ANALYSIS ; HAPLOTYPE MAP ; PROJECT ; KEGG ; HISTORY ; COMMON ; TRANSFERABILITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000320362700111 |
| 源URL | [http://124.16.173.210/handle/834782/1242]  |
| 专题 | 天津工业生物技术研究所_基因组分析实验室 陈祖耕_期刊论文 |
| 作者单位 | 1.Harbin Med Univ, Coll Bioinformat Sci & Technol, Harbin, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China 3.Cent S Univ, Sch Publ Hlth, Dept Epidemiol & Stat, Changsha, Hunan, Peoples R China 4.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Yongshuai,Zhang, Ruijie,Lv, Hongchao,et al. HGPGD: The Human Gene Population Genetic Difference Database[J]. PLOS ONE,2013,8(5). |
| APA | Jiang, Yongshuai.,Zhang, Ruijie.,Lv, Hongchao.,Li, Jin.,Wang, Miao.,...&Liu, Guiyou.(2013).HGPGD: The Human Gene Population Genetic Difference Database.PLOS ONE,8(5). |
| MLA | Jiang, Yongshuai,et al."HGPGD: The Human Gene Population Genetic Difference Database".PLOS ONE 8.5(2013). |
入库方式： OAI收割
来源：天津工业生物技术研究所
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