Efficient Open Fermentative Production of Polymer-Grade L-Lactate from Sugarcane Bagasse Hydrolysate by Thermotolerant Bacillus sp Strain P38
文献类型：期刊论文
| 作者 | Peng, Lili1; Xie, Nengzhong2; Guo, Ling2; Wang, Limin1; Yu, Bo1; Ma, Yanhe3 |
| 刊名 | PLOS ONE
 |
| 出版日期 | 2014-09-05 |
| 卷号 | 9期号:9 |
| 英文摘要 | Lactic acid is one of the top 30 potential building-block chemicals from biomass, of which the most extensive use is in the polymerization of lactic acid to poly-lactic-acid (PLA). To reduce the cost of PLA, the search for cheap raw materials and low-cost process for lactic acid production is highly desired. In this study, the final titer of produced L-lactic acid reached a concentration of 185 g.L-1 with a volumetric productivity of 1.93 g.L-1.h(-1) by using sugarcane bagasse hydrolysate as the sole carbon source simultaneously with cottonseed meal as cheap nitrogen sources under the open fed-batch fermentation process. Furthermore, a lactic acid yield of 0.99 g per g of total reducing sugars was obtained, which is very close to the theoretical value (1.0 g.g(-1)). No D-isomer of lactic acid was detected in the broth, and thereafter resulted in an optical purity of 100%, which exceeds the requirement of lactate polymerization process. To our knowledge, this is the best performance of fermentation on polymer-grade L-lactic acid production totally using lignocellulosic sources. The high levels of optically pure L-lactic acid produced, combined with the ease of handling and low costs associated with the open fermentation strategy, indicated the thermotolerant Bacillus sp. P38 could be an excellent candidate strain with great industrial potential for polymer-grade L-lactic acid production from various cellulosic biomasses. |
| WOS标题词 | Science & Technology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | LACTIC-ACID PRODUCTION ; SIMULTANEOUS SACCHARIFICATION ; HEMICELLULOSE HYDROLYSATE ; LACTOBACILLUS-CASEI ; L(+)-LACTIC ACID ; NITROGEN-SOURCES ; CELLULOSE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347993600101 |
| 源URL | [http://124.16.173.210/handle/834782/1420]  |
| 专题 | 天津工业生物技术研究所_酶工程实验室 马延和 _期刊论文 |
| 作者单位 | 1.Chinese Acad Sci, Inst Microbiol, CAS Key Lab Microbial Physiol & Metab Engn, Beijing, Peoples R China 2.Guangxi Acad Sci, Natl Engn Res Ctr Nonfood Biorefinery, Nanning, Peoples R China 3.Chinese Acad Sci, Tianjin Inst Ind Biotechnol, Tianjin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Peng, Lili,Xie, Nengzhong,Guo, Ling,et al. Efficient Open Fermentative Production of Polymer-Grade L-Lactate from Sugarcane Bagasse Hydrolysate by Thermotolerant Bacillus sp Strain P38[J]. PLOS ONE,2014,9(9). |
| APA | Peng, Lili,Xie, Nengzhong,Guo, Ling,Wang, Limin,Yu, Bo,&Ma, Yanhe.(2014).Efficient Open Fermentative Production of Polymer-Grade L-Lactate from Sugarcane Bagasse Hydrolysate by Thermotolerant Bacillus sp Strain P38.PLOS ONE,9(9). |
| MLA | Peng, Lili,et al."Efficient Open Fermentative Production of Polymer-Grade L-Lactate from Sugarcane Bagasse Hydrolysate by Thermotolerant Bacillus sp Strain P38".PLOS ONE 9.9(2014). |
入库方式： OAI收割
来源：天津工业生物技术研究所
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