Diastereoselective and Enantioselective Synthesis of Unsymmetric beta,beta-Diaryl-alpha-Amino Acid Esters via Organocatalytic 1,6-Conjugate Addition of para-Quinone Methides
文献类型：期刊论文
| 作者 | Zhang, Xiang-Zhi1; Deng, Yu-Hua3; Yan, Xu1; Yu, Ke-Yin1; Wang, Fang-Xin1; Ma, Xiao-Yan1; Fan, Chun-An1,2 |
| 刊名 | Journal of Organic Chemistry
 |
| 出版日期 | 2016 |
| 卷号 | 81期号:13页码:5655-5662 |
| ISSN号 | 0022-3263 |
| 英文摘要 | A novel strategy based on phase transfer catalysis for the diastereoselective and enantioselective direct assembly of unsymmetric beta,beta-diaryl-alpha-amino acid esters via 1,6-conjugate addition of para-quinone methides and glycine derivatives is described. This protocol also provides an alternative route to the synthetically interesting functionalized chiral tetrahydroisoquinoline and its analogues. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (21572083;21322201;21290180);the Fundamental Research Funds for the Central Universities (lzujbky-2015-58);the State Key Laboratory of Natural and Biomimetic Drugs (K20150213);PCSIRT (IRT-15R28);the 111 Project of Ministry of Education of China (111-2-17);Chang Jiang Scholars Program (C.A.F.) |
| 语种 | 英语 |
| WOS记录号 | WOS:000379456500041 |
| 源URL | [http://210.77.64.217/handle/362003/20197]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, 222 Tianshui Nanlu, Lanzhou 730000, Peoples R China 2.Peking Univ, State Key Lab Nat & Biomimet Drugs, 38 Xueyuan Lu, Beijing 100191, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Xiang-Zhi,Deng, Yu-Hua,Yan, Xu,et al. Diastereoselective and Enantioselective Synthesis of Unsymmetric beta,beta-Diaryl-alpha-Amino Acid Esters via Organocatalytic 1,6-Conjugate Addition of para-Quinone Methides[J]. Journal of Organic Chemistry,2016,81(13):5655-5662. |
| APA | Zhang, Xiang-Zhi.,Deng, Yu-Hua.,Yan, Xu.,Yu, Ke-Yin.,Wang, Fang-Xin.,...&Fan, Chun-An.(2016).Diastereoselective and Enantioselective Synthesis of Unsymmetric beta,beta-Diaryl-alpha-Amino Acid Esters via Organocatalytic 1,6-Conjugate Addition of para-Quinone Methides.Journal of Organic Chemistry,81(13),5655-5662. |
| MLA | Zhang, Xiang-Zhi,et al."Diastereoselective and Enantioselective Synthesis of Unsymmetric beta,beta-Diaryl-alpha-Amino Acid Esters via Organocatalytic 1,6-Conjugate Addition of para-Quinone Methides".Journal of Organic Chemistry 81.13(2016):5655-5662. |
入库方式： OAI收割
来源：兰州化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。