Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling
文献类型：期刊论文
| 作者 | Lu, Xi1,2,3; Yi, Jun1; Zhang, Zhen-Qi1; Dai, Jian-Jun1; Liu, Jing-Hui1; Xiao, Bin1; Fu, Yao1; Liu, Lei1,2,3 |
| 刊名 | Chemistry - A European Journal
 |
| 出版日期 | 2014 |
| 卷号 | 20期号:47页码:15339-15343 |
| 关键词 | amino acids catalysis C-C bond formation nickel reductive cross-coupling |
| ISSN号 | 0947-6539 |
| 通讯作者 | Xiao, Bin ; Liu, Lei |
| 英文摘要 | A novel method for the synthesis of non-natural L- and D-amino acids by a Ni-catalyzed reductive cross-coupling reaction is described. This strategy enables the racemization-free cross-coupling of serine/homoserine-derived iodides with aryl/acyl/alkyl halides. It provides convenient access to varieties of enantiopure and functionalized amino acids, which are important building blocks in bioactive compounds and pharmaceuticals. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the "863" Program of the Ministry of Science and Technology (2012AA02A700);the National Basic Research Program of China (973 program, No. 2013CB932800);NSFC (Nos. 21472181;91313301;21221062);SRFDP (20133402120034) |
| 语种 | 英语 |
| WOS记录号 | WOS:000345234800011 |
| 源URL | [http://210.77.64.217/handle/362003/20286]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 3.Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lu, Xi,Yi, Jun,Zhang, Zhen-Qi,et al. Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling[J]. Chemistry - A European Journal,2014,20(47):15339-15343. |
| APA | Lu, Xi.,Yi, Jun.,Zhang, Zhen-Qi.,Dai, Jian-Jun.,Liu, Jing-Hui.,...&Liu, Lei.(2014).Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling.Chemistry - A European Journal,20(47),15339-15343. |
| MLA | Lu, Xi,et al."Expedient Synthesis of Chiral alpha-Amino Acids through Nickel-Catalyzed Reductive Cross-Coupling".Chemistry - A European Journal 20.47(2014):15339-15343. |
入库方式： OAI收割
来源：兰州化学物理研究所
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