Asymmetric Synthesis of CF3- and Indole-Containing Thiochromanes via a Squaramide-Catalyzed Michael-Aldol Reaction
文献类型：期刊论文
| 作者 | Zhu, Yuanyuan1; Dong, Zhenghao1; Cheng, Xin1; Zhong, Xiaoling1; Liu, Xiaolin1; Lin, Li1; Shen ZQ(沈志强)2 ; Yang PJ(杨培菊)2; Li, Yuan3; Wang, Hailin3
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| 刊名 | Organic Letters
 |
| 出版日期 | 2016 |
| 卷号 | 18期号:15页码:3546-3549 |
| ISSN号 | 1523-7060 |
| 通讯作者 | Yan, Wenjin ; Wang, Kairong ; 王锐 |
| 英文摘要 | A Michael–aldol reaction of 2-mercaptobenzaldehyde with β-indole-β-CF3 enones catalyzed by a squaramide has been realized. The method affords a series of 2-CF3-2-indole-substituted thiochromanes featuring a CF3-containing quaternary stereocenter in excellent yields, diastereoselectivities, and enantioselectivities. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (21432003;21272107;21272108;81260387;81360112;81573265);the Fundamental Research Funds for the Central Universities (lzujbky-2015-155;lzujbky-2015-279) |
| 语种 | 英语 |
| WOS记录号 | WOS:000381236300010 |
| 源URL | [http://210.77.64.217/handle/362003/20308]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.Lanzhou Univ, Inst Pharmacol, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic,Med Sci, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 3.Peoples Hosp Gansu Prov, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Yuanyuan,Dong, Zhenghao,Cheng, Xin,et al. Asymmetric Synthesis of CF3- and Indole-Containing Thiochromanes via a Squaramide-Catalyzed Michael-Aldol Reaction[J]. Organic Letters,2016,18(15):3546-3549. |
| APA | Zhu, Yuanyuan.,Dong, Zhenghao.,Cheng, Xin.,Zhong, Xiaoling.,Liu, Xiaolin.,...&Wang R.(2016).Asymmetric Synthesis of CF3- and Indole-Containing Thiochromanes via a Squaramide-Catalyzed Michael-Aldol Reaction.Organic Letters,18(15),3546-3549. |
| MLA | Zhu, Yuanyuan,et al."Asymmetric Synthesis of CF3- and Indole-Containing Thiochromanes via a Squaramide-Catalyzed Michael-Aldol Reaction".Organic Letters 18.15(2016):3546-3549. |
入库方式： OAI收割
来源：兰州化学物理研究所
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