An electrochemical immunosensor for quantitative detection of ficolin-3
文献类型：期刊论文
| 作者 | San, LL; Zeng, DD; Song, SP; Zuo, XL; Zhang, H; Wang, CG; Wu, JR; Mi, XQ |
| 刊名 | NANOTECHNOLOGY
 |
| 出版日期 | 2016 |
| 卷号 | 27期号:25页码:— |
| 关键词 | SYSTEMIC-LUPUS-ERYTHEMATOSUS IMMUNE COMPONENT FICOLIN-3 TYPE-2 DIABETES-MELLITUS GLASSY-CARBON ELECTRODE HAKATA ANTIGEN INSULIN-RESISTANCE COMPETITIVE ELISA AFLATOXIN B-1 SERUM-LEVELS IDENTIFICATION |
| ISSN号 | 0957-4484 |
| 通讯作者 | Wu, JR (reprint author), Chinese Acad Sci, Shanghai Adv Res Inst, Lab Syst Biol, Shanghai 201210, Peoples R China. ; Wu, JR (reprint author), Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Biochem & Cell Biol, Key Lab Syst Biol, Shanghai 200031, Peoples R China. |
| 英文摘要 | Diabetes mellitus (DM) is one of the most common metabolic disorders in the world, of which more than 90% is type-2 diabetes mellitus (T2DM). There is a rather urgent need for reliable, sensitive and quick detection techniques in clinical application of T2DM. Ficolin-3 is a potential biomarker of T2DM, because serum ficolin-3 levels are associated with insulin resistance and predict the incidence of T2DM. Herein, a sandwich-type electrochemical immunosensor was developed for the detection of ficolin-3 in human serum. Cyclic voltammetry and the amperometric current versus time were used to characterize the performance of the immunosensor. Under optimal conditions, the detection limitation of ficolin-3 was 100 ng ml(-1) and the linear dynamic range was between 2 and 50 mu g ml(-1). The method has ideal accuracy, excellent stability and selectivity and has wide application prospects in clinical research. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000377064200004 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/25643]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | San, LL,Zeng, DD,Song, SP,et al. An electrochemical immunosensor for quantitative detection of ficolin-3[J]. NANOTECHNOLOGY,2016,27(25):—. |
| APA | San, LL.,Zeng, DD.,Song, SP.,Zuo, XL.,Zhang, H.,...&Mi, XQ.(2016).An electrochemical immunosensor for quantitative detection of ficolin-3.NANOTECHNOLOGY,27(25),—. |
| MLA | San, LL,et al."An electrochemical immunosensor for quantitative detection of ficolin-3".NANOTECHNOLOGY 27.25(2016):—. |
入库方式： OAI收割
来源：上海应用物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。